Dopamine receptors are widely distributed within the brain where they play critical
modulator roles on motor functions, motivation and drive, as well as cognition. The …

Spike-timing-dependent synaptic plasticity (STDP) is a leading cellular model for behavioral
learning and memory with rich computational properties. However, the relationship between …

Spike timing-dependent plasticity (STDP) is a bidirectional form of synaptic plasticity
discovered about 30 years ago and based on the relative timing of pre-and post-synaptic …

Neural computational power is determined by neuroenergetics, but how and which energy
substrates are allocated to various forms of memory engram is unclear. To solve this …

The molecular pathways underlying the induction and maintenance of long-term synaptic
plasticity have been extensively investigated revealing various mechanisms by which …

Highlights•Hebbian protocols induce bidirectional plasticity (LTP and LTD) in the
striatum.•Multiple pathways interact to induce activity-dependent STDP in the …

Highlights•Metaplasticity phenomena underlie the state-dependency of synaptic
plasticity.•Activation and trafficking of glutamate receptors underpin metaplasticity …

The endocannabinoid (eCB) system is a lipid-based neurotransmitter complex that plays
crucial roles in the neural control of learning and memory. The current model of eCB …

The basal ganglia network is represented by an interconnected group of subcortical nuclei
traditionally thought to play a crucial role in motor learning and movement execution. During …

von Monakow's theory of diaschisis states the functional 'standstill'of intact brain regions that
are remote from a damaged area, often implied in recovery of function. Accordingly, neural …