Opportunities and challenges in enhancing the bioavailability and bioactivity of dietary flavonoids: A novel delivery system perspective
D Yuan, Y Guo, F Pu, C Yang, X **ao, H Du, J He, S Lu - Food Chemistry, 2024 - Elsevier
Flavonoids have multiple favorable bioactivities including antioxidant, anti-inflammatory, and
antitumor. Currently, flavonoid-containing dietary supplements are widely tested in clinical …
antitumor. Currently, flavonoid-containing dietary supplements are widely tested in clinical …
Deep Eutectic Solvents: An Eco‐friendly Design for Drug Engineering
In the spirit of circular economy and sustainable chemistry, the use of environmentally
friendly chemical products in pharmacy has become a hot topic. In recent years, organic …
friendly chemical products in pharmacy has become a hot topic. In recent years, organic …
Fisetin—In search of better bioavailability—From macro to nano modifications: A review
As secondary plant metabolites, polyphenols are abundant in fruits and vegetables. They
are in high demand because of their many health benefits. However, their low bioavailability …
are in high demand because of their many health benefits. However, their low bioavailability …
Kaempferol and fisetin-related signaling pathways induce apoptosis in head and neck cancer cells
Despite the relative effectiveness of standard cancer treatment strategies, head and neck
cancer (HNC) is still considered one of the leading causes of mortality and morbidity. While …
cancer (HNC) is still considered one of the leading causes of mortality and morbidity. While …
A Fisetin Delivery System for Neuroprotection: A Co-Amorphous Dispersion Prepared in Supercritical Carbon Dioxide
Fisetin (FIS), a senolytic flavonoid, mitigates age-related neuroprotective changes. An
amorphous FIS dispersion with a co-carrier was prepared using supercritical fluid extraction …
amorphous FIS dispersion with a co-carrier was prepared using supercritical fluid extraction …
Drug nanocrystals: Surface engineering and its applications in targeted delivery
P Lhaglham, L Jiramonai, Y Jia, B Huang, Y Huang… - iScience, 2024 - cell.com
Drug nanocrystals have received significant attention in drug development due to their
enhanced dissolution rate and improved water solubility, making them effective in …
enhanced dissolution rate and improved water solubility, making them effective in …
Nanoparticle-based flavonoid therapeutics: Pioneering biomedical applications in antioxidants, cancer treatment, cardiovascular health, neuroprotection, and …
HM Morsy, MY Zaky, NYS Yassin… - International Journal of …, 2024 - Elsevier
Flavonoids, a type of natural polyphenolic molecule, have garnered significant research
interest due to their ubiquitous nature and diverse biological activities, including antioxidant …
interest due to their ubiquitous nature and diverse biological activities, including antioxidant …
[HTML][HTML] A novel temperature-controlled media milling device to produce drug nanocrystals at the laboratory scale
Poor aqueous solubility of preexisting and emerging drug molecules is a common issue
faced in the field of pharmaceutics. To address this, particle size reduction techniques …
faced in the field of pharmaceutics. To address this, particle size reduction techniques …
Quality by design-oriented formulation optimization and characterization of guar gum-pectin based oral colon targeted liquisolid formulation of xanthohumol
S Chatterjee, L Corrie, M Hanmantrao… - Journal of Drug Delivery …, 2023 - Elsevier
In the present study a colon targeted liquisolid powder of xanthohumol was developed using
Central Composite Design (CCD). Xanthohumol is a drug obtained from hops plants that …
Central Composite Design (CCD). Xanthohumol is a drug obtained from hops plants that …
Glucose-capped fisetin silver nanoparticles induced cytotoxicity and ferroptosis in breast cancer cells: a molecular perspective
K Subhalakshmi, VP Veeraraghavan… - Inorganic Chemistry …, 2024 - Elsevier
Breast cancer is a prevalent malignancy that poses a significant health threat globally
among the women population. In this study, we sought to investigate the cytotoxic and …
among the women population. In this study, we sought to investigate the cytotoxic and …