In recent years, significant conceptual advances have taken place in the field of amide bond
cross-coupling. Mild and selective functionalization of amides by transition-metal catalysis …

The ability to control the reactions of highly active chemical species to enable
straightforward synthesis of valuable compounds such as bioactive natural products and …

We report a divergent and modular protocol for the preparation of acyclic molecular
frameworks containing newly created quaternary carbon stereocenters. Central to this …

A Ni-catalyzed decarbonylative methylation of aromatic esters was achieved using
methylaluminums as methylating agents. Dimethylaluminum chlorides uniquely worked as …

Amides are among the most important and ubiquitous functional groups in organic chemistry
and process development. In this Practical Synthetic Procedure, a protocol for the Suzuki …

We developed the first carbenoid insertion reaction into the urea C− N bond. The urea
insertion reaction proceeded smoothly using Rh 2 (NHPiv) 4, a rhodium catalyst previously …

Mild solvolytic cleavage of bis (2-pyridyl) amide under neutral and room-temperature
conditions is described. The inherently stable amide was readily activated by catalytic …