[HTML][HTML] A pragmatic guide to enrichment strategies for mass spectrometry–based glycoproteomics

NM Riley, CR Bertozzi, SJ Pitteri - Molecular & Cellular Proteomics, 2021 - Elsevier
Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …

[HTML][HTML] Aberrant protein glycosylation: Implications on diagnosis and Immunotherapy

R Bangarh, C Khatana, S Kaur, A Sharma… - Biotechnology …, 2023 - Elsevier
Glycosylation-mediated post-translational modification is critical for regulating many
fundamental processes like cell division, differentiation, immune response, and cell-to-cell …

FUT8 alpha-(1, 6)-fucosyltransferase in cancer

K Bastian, E Scott, DJ Elliott, J Munkley - International Journal of …, 2021 - mdpi.com
Aberrant glycosylation is a universal feature of cancer cells that can impact all steps in
tumour progression from malignant transformation to metastasis and immune evasion. One …

Recent advances in glycoproteomic analysis by mass spectrometry

S Suttapitugsakul, F Sun, R Wu - Analytical chemistry, 2019 - ACS Publications
Glycosylation is one of the most common protein modifications and is essential for cells. This
modification is exceptionally complex because glycans are highly diverse and can be …

Glycans as biomarkers in prostate cancer

E Scott, J Munkley - International journal of molecular sciences, 2019 - mdpi.com
Prostate cancer is the most commonly diagnosed malignancy in men, claiming over 350,000
lives worldwide annually. Current diagnosis relies on prostate-specific antigen (PSA) testing …

[HTML][HTML] Meta-heterogeneity: evaluating and describing the diversity in glycosylation between sites on the same glycoprotein

T Čaval, AJR Heck, KR Reiding - Molecular & Cellular Proteomics, 2021 - Elsevier
Mass spectrometry–based glycoproteomics has gone through some incredible
developments over the last few years. Technological advances in glycopeptide enrichment …

Plant‐derived lectins as potential cancer therapeutics and diagnostic tools

M Mazalovska, JC Kouokam - BioMed Research International, 2020 - Wiley Online Library
Cancer remains a global health challenge, with high morbidity and mortality, despite the
recent advances in diagnosis and treatment. Multiple compounds assessed as novel …

Recent advances in analytical approaches for glycan and glycopeptide quantitation

DG Delafield, L Li - Molecular & Cellular Proteomics, 2021 - Elsevier
Growing implications of glycosylation in physiological occurrences and human disease have
prompted intensive focus on revealing glycomic perturbations through absolute and relative …

The Hitchhiker's guide to glycoproteomics

T Oliveira, M Thaysen-Andersen… - Biochemical Society …, 2021 - portlandpress.com
Protein glycosylation is one of the most common post-translational modifications that are
essential for cell function across all domains of life. Changes in glycosylation are considered …

Characterization of core fucosylation via sequential enzymatic treatments of intact glycopeptides and mass spectrometry analysis

L Cao, TM Lih, Y Hu, M Schnaubelt, SY Chen… - Nature …, 2022 - nature.com
Core fucosylation of N-linked glycoproteins has been linked to the functions of glycoproteins
in physiological and pathological processes. However, quantitative characterization of core …