A human urothelial microtissue model reveals shared colonization and survival strategies between uropathogens and commensals

C Flores, J Ling, A Loh, RG Maset, A Aw, IJ White… - Science …, 2023‏ - science.org
Urinary tract infection is among the most common infections worldwide, typically studied in
animals and cell lines with limited uropathogenic strains. Here, we assessed diverse …

Asymptomatic Bacteriuria in Kidney Transplant Recipients—A Narrative Review

JE Gołębiewska, B Krawczyk, M Wysocka, A Dudziak… - Medicina, 2023‏ - mdpi.com
Urinary tract infections (UTIs) are the most prevalent complications in kidney transplant (KTx)
recipients. The most frequent finding in this group of patients is asymptomatic bacteriuria …

“Omics” Technologies - What Have They Told Us About Uropathogenic Escherichia coli Fitness and Virulence During Urinary Tract Infection?

S Torres-Puig, V García, K Stærk… - Frontiers in cellular …, 2022‏ - frontiersin.org
Uropathogenic Escherichia coli (UPEC) is the main etiological agent of urinary tract infection
(UTI), a widespread infectious disease of great impact on human health. This is further …

The role of mobile genetic elements in virulence factor carriage from symptomatic and asymptomatic cases of Escherichia coli bacteriuria

G Morales, B Abelson, S Reasoner, J Miller… - Microbiology …, 2023‏ - journals.asm.org
Uropathogenic Escherichia coli (UPEC) is extremely diverse genotypically and
phenotypically. Individual strains can variably carry diverse virulence factors, making it …

Fluorothiazinon inhibits the virulence factors of uropathogenic Escherichia coli involved in the development of urinary tract infection

EA Koroleva, AV Soloveva, EY Morgunova… - The Journal of …, 2023‏ - nature.com
Uropathogenic Escherichia coli (UPEC) is the most common pathogenic bacterium
associated with urinary tract infection. Due to the development of antibiotic resistance and …

[HTML][HTML] Asymptomatic bacteriuria (ABU) in elderly: prevalence, virulence, phylogeny, antibiotic resistance and complement C3 in urine

RF Leihof, KL Nielsen, N Frimodt-Møller - Microorganisms, 2021‏ - mdpi.com
Background: The incidence of asymptomatic bacteriuria (ABU) increases with age and is
most common for persons 80 years of age and above and in elderly living in nursing homes …

[HTML][HTML] Intra-strain colony biofilm heterogeneity in uropathogenic Escherichia coli and the effect of the NlpI lipoprotein

HD Green, GT Van Horn, T Williams, A Eberly… - Biofilm, 2024‏ - Elsevier
Biofilm growth facilitates the interaction of uropathogenic Escherichia coli (UPEC) with the
host environment. The extracellular polymeric substances (EPS) of UPEC biofilms are …

Adaptation of arginine synthesis among uropathogenic branches of the Escherichia coli phylogeny reveals adjustment to the urinary tract habitat

ME Hibbing, KW Dodson, V Kalas, SL Chen… - MBio, 2020‏ - journals.asm.org
Urinary tract infections (UTIs) are predominantly caused by uropathogenic Escherichia coli
(UPEC). UPEC pathogenesis requires passage through a severe population bottleneck …

Urinary tract infections as a continuum: implications for diagnostic and antibiotic stewardship

BW Trautner - Clinical Infectious Diseases, 2021‏ - academic.oup.com
An outpatient urinary tract infection (UTI) is such a common clinical scenario that
understanding the difference between a symptomatic UTI and asymptomatic bacteriuria …

[HTML][HTML] Metabolomic analysis evidences that uterine epithelial cells enhance blastocyst development in a microfluidic device

V Mancini, AC Schrimpe-Rutledge, SG Codreanu… - Cells, 2021‏ - mdpi.com
Here we report the use of a microfluidic system to assess the differential metabolomics of
murine embryos cultured with endometrial cells-conditioned media (CM). Groups of 10, 1 …