Heterocyclic Schiff base transition metal complexes in antimicrobial and anticancer chemotherapy

MA Malik, OA Dar, P Gull, MY Wani, AA Hashmi - MedChemComm, 2018 - pubs.rsc.org
In recent years, the number of people suffering from cancer and multidrug-resistant
infections has sharply increased, leaving humanity without any choice but to search for new …

Advances in copper complexes as anticancer agents

C Santini, M Pellei, V Gandin, M Porchia… - Chemical …, 2014 - ACS Publications
Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …

Exploration of the medical periodic table: towards new targets

NPE Barry, PJ Sadler - Chemical Communications, 2013 - pubs.rsc.org
Metallodrugs offer potential for unique mechanisms of drug action based on the choice of
the metal, its oxidation state, the types and number of coordinated ligands and the …

Bovine serum albumin interactions with metal complexes

T Topală, A Bodoki, L Oprean, R Oprean - Clujul medical, 2014 - pmc.ncbi.nlm.nih.gov
The continuous search for new molecules with therapeutic abilities has led to the synthesis
and characterization of a large number of metal complexes, proven to exhibit potential as …

A novel water soluble ligand bridged cobalt (II) coordination polymer of 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde (isonicotinic) hydrazone: evaluation of the DNA …

DS Raja, NSP Bhuvanesh, K Natarajan - Dalton Transactions, 2012 - pubs.rsc.org
A novel water soluble ligand-bridged cobalt (II) coordination polymer has been synthesized
by reacting the new ligand, 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde (isonicotinic) …

Synthesis, DNA/protein binding, molecular docking, DNA cleavage and in vitro anticancer activity of nickel (II) bis (thiosemicarbazone) complexes

J Haribabu, K Jeyalakshmi, Y Arun, NSP Bhuvanesh… - RSC Advances, 2015 - pubs.rsc.org
A series of N-substituted isatin thiosemicarbazone ligands (L1–L5) and their nickel (II)
complexes [Ni (L) 2](1–5) were synthesized and characterized by elemental analyses and …

Potentially cytotoxic new copper (II) hydrazone complexes: synthesis, crystal structure and biological properties

M Alagesan, NSP Bhuvanesh, N Dharmaraj - Dalton Transactions, 2013 - pubs.rsc.org
A new set of penta-coordinated copper (II) hydrazone complexes containing solvated
methanol were synthesized by reacting the hydrazone ligands, 2-acetylpyridine benzoyl …

Anti-cancer property and DNA binding interaction of first row transition metal complexes: a decade update

U Dasmahapatra, B Maiti, MM Alam… - European Journal of …, 2024 - Elsevier
Metal ions carry out a wide variety of functions, including acid-base/redox catalysis,
structural functions, signaling, and electron transport. Understanding the interactions of …

Effect of N (4)-phenyl substitution in 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde semicarbazones on the structure, DNA/protein interaction, and antioxidative and …

D Senthil Raja, NSP Bhuvanesh… - Inorganic Chemistry, 2011 - ACS Publications
A new ligand, 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde semicarbazone (OQsc-H)(1);, its
N (4)-phenyl derivative (OQsc-Ph)(2); and their corresponding copper (II) complexes [CuCl2 …