Results from recent clinical trials of antibodies that target amyloid-β (Aβ) for Alzheimer's
disease have created excitement and have been heralded as corroboration of the amyloid …

Polymorphism in the apolipoprotein E (APOE) gene is a major genetic risk determinant of
late-onset Alzheimer disease (AD), with the APOE* ε 4 allele conferring an increased risk …

Importance Trends in type 2 diabetes show an increase in prevalence along with younger
age of onset. While vascular complications of early-onset type 2 diabetes are known, the …

Insulin plays a range of roles as an anabolic hormone in peripheral tissues. It regulates
glucose metabolism, stimulates glucose transport into cells and suppresses hepatic glucose …

Considerable overlap has been identified in the risk factors, comorbidities and putative
pathophysiological mechanisms of Alzheimer disease and related dementias (ADRDs) and …

Alzheimer's disease (AD) is the most common form of dementia. However, the
etiopathogenesis of this devastating disease is not fully understood. Recent studies in …

Abstract Objective (Background): Alzheimer's disease (AD), clinically characterized by the
progressive neurodegenerative condition and cognitive impairment, is one of the main …

Context: Gut dysbiosis has been proposed as one of pathologies in patients with Alzheimer's
disease (AD) spectrum. Despite such enthusiasm, the relevant results remain substantially …

Background: It is widely known that the harmful effects of fine dust can cause various
diseases. Research on the correlation between fine dust and health has been mainly …

Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …