Specialized subpopulations of CD4+ T cells survey major histocompatibility complex class II–
peptide complexes to control phagosomal infections, help B cells, regulate tissue …

Recent advances in studies of immune memory in mice and humans have reinforced the
concept that memory B cells play a critical role in protection against repeated infections …

Immune memory—comprising T cells, B cells and plasma cells and their secreted antibodies—
is crucial for human survival. It enables the rapid and effective clearance of a pathogen after …

Mpox virus (MPXV) caused a multi-country outbreak in non-endemic areas in 2022.
Following historic success of smallpox vaccination with vaccinia virus (VACV)-based …

Memory T and B cells in tissues are essential for protective immunity. Here, we performed a
comprehensive analysis of the tissue distribution, phenotype, durability, and transcriptional …

Immunological memory protects the human body from re-infection with an earlier recognized
pathogen. This memory comprises the durable serum antibody titres provided by long-lived …

The long-lasting humoral immunity induced by viral infections or vaccinations depends on
memory B cells with greatly increased affinity to viral antigens, which are evolved from …

Protective immunity following vaccination is sustained by long-lived antibody-secreting cells
and resting memory B cells (MBCs). Responses to two-dose SARS-CoV-2 mRNA-1273 …

Several species generate their preimmune repertoire in gut-associated lymphoid tissues
(GALT), compensating a reduced germline V gene repertoire by post-rearrangement …

Expression of the transcriptional regulator ZFP318 is induced in germinal center (GC)-
exiting memory B cell precursors and memory B cells (MBCs). Using a conditional ZFP318 …