Bidirectional regulation of cognitive and anxiety-like behaviors by dentate gyrus mossy cells in male and female mice
The dentate gyrus (DG) of the hippocampus is important for cognition and behavior.
However, the circuits underlying these functions are unclear. DG mossy cells (MCs) are …
However, the circuits underlying these functions are unclear. DG mossy cells (MCs) are …
Dorsal and ventral mossy cells differ in their axonal projections throughout the dentate gyrus of the mouse hippocampus
Glutamatergic hilar mossy cells (MCs) have axons that terminate both near and far from their
cell body but stay within the DG, making synapses primarily in the molecular layer. The long …
cell body but stay within the DG, making synapses primarily in the molecular layer. The long …
[HTML][HTML] Early changes in synaptic and intrinsic properties of dentate gyrus granule cells in a mouse model of Alzheimer's disease neuropathology and atypical effects …
It has been reported that hyperexcitability occurs in a subset of patients with Alzheimer's
disease (AD) and hyperexcitability could contribute to the disease. Several studies have …
disease (AD) and hyperexcitability could contribute to the disease. Several studies have …
[HTML][HTML] Modeling intrahippocampal effects of anterior hippocampal hyperactivity relevant to schizophrenia using chemogenetic excitation of long axis–projecting …
JP Bauer, SL Rader, ME Joffe, W Kwon, J Quay… - … psychiatry global open …, 2021 - Elsevier
Background The anterior hippocampus of individuals with early psychosis or schizophrenia
is hyperactive, as is the ventral hippocampus in many rodent models for schizophrenia risk …
is hyperactive, as is the ventral hippocampus in many rodent models for schizophrenia risk …
Increased excitability of dentate gyrus mossy cells occurs early in life in the Tg2576 model of Alzheimer's disease
ABSTRACT INTRODUCTION Hyperexcitability in Alzheimer's disease (AD) emerge early
and contribute to disease progression. The dentate gyrus (DG) is implicated in …
and contribute to disease progression. The dentate gyrus (DG) is implicated in …
Dorsal and ventral mossy cells differ in their long-range axonal projections throughout the dentate gyrus of the mouse hippocampus
JJ Botterill, KJ Gerencer, KY Vinod… - bioRxiv, 2020 - biorxiv.org
Glutamatergic hilar mossy cells (MCs) have axons that terminate both near and far from their
cell body but stay within the DG, making synapses in the inner molecular layer primarily. The …
cell body but stay within the DG, making synapses in the inner molecular layer primarily. The …
Transformation of spatial representations along the mouse hippocampal circuits
B Gandit - 2021 - theses.hal.science
Forming a precise memory of our spatial environment is essential for our survival, as we
depend on our ability to store and recall important locations. The hippocampus is thought to …
depend on our ability to store and recall important locations. The hippocampus is thought to …