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Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities
Atherosclerosis is a lipid-driven inflammatory disease of the arterial intima in which the
balance of pro-inflammatory and inflammation-resolving mechanisms dictates the final …
balance of pro-inflammatory and inflammation-resolving mechanisms dictates the final …
Efferocytosis in atherosclerosis
Cardiovascular disease is the leading cause of death worldwide, and it commonly results
from atherosclerotic plaque progression. One of the increasingly recognized drivers of …
from atherosclerotic plaque progression. One of the increasingly recognized drivers of …
Association analyses based on false discovery rate implicate new loci for coronary artery disease
Genome-wide association studies (GWAS) in coronary artery disease (CAD) had identified
66 loci at'genome-wide significance'(P< 5× 10− 8) at the time of this analysis, but a much …
66 loci at'genome-wide significance'(P< 5× 10− 8) at the time of this analysis, but a much …
Mechanisms and consequences of defective efferocytosis in atherosclerosis
Efficient clearance of apoptotic cells, termed efferocytosis, critically regulates normal
homeostasis whereas defective uptake of apoptotic cells results in chronic and non …
homeostasis whereas defective uptake of apoptotic cells results in chronic and non …
Consideration of sex differences in design and reporting of experimental arterial pathology studies—statement from ATVB council
P Robinet, DM Milewicz, LA Cassis… - … , and vascular biology, 2018 - ahajournals.org
There are many differences in arterial diseases between men and women, including
prevalence, clinical manifestations, treatments, and prognosis. The new policy of the …
prevalence, clinical manifestations, treatments, and prognosis. The new policy of the …
The role of efferocytosis in atherosclerosis
The necrotic core has long been a hallmark of the vulnerable atherosclerotic plaque.
Although apoptotic cells are cleared quickly in almost all other tissue beds, their removal …
Although apoptotic cells are cleared quickly in almost all other tissue beds, their removal …
Selection of metastasis competent subclones in the tumour interior
The genetic evolutionary features of solid tumour growth are becoming increasingly well
described, but the spatial and physical nature of subclonal growth remains unclear. Here …
described, but the spatial and physical nature of subclonal growth remains unclear. Here …
Clonally expanding smooth muscle cells promote atherosclerosis by esca** efferocytosis and activating the complement cascade
Y Wang, V Nanda, D Direnzo, J Ye, S **ao… - Proceedings of the …, 2020 - pnas.org
Atherosclerosis is the process underlying heart attack and stroke. Despite decades of
research, its pathogenesis remains unclear. Dogma suggests that atherosclerotic plaques …
research, its pathogenesis remains unclear. Dogma suggests that atherosclerotic plaques …
Efferocytosis in atherosclerotic lesions: Malfunctioning regulatory pathways and control mechanisms
Atherosclerosis is a dynamic and progressive inflammatory process in the intimal layer of
large and medium-sized arteries, and it is the major contributor to the atherosclerotic …
large and medium-sized arteries, and it is the major contributor to the atherosclerotic …
The role of ANRIL in atherosclerosis
I Razeghian-Jahromi, A Karimi Akhormeh… - Disease …, 2022 - Wiley Online Library
There is a huge number of noncoding RNA (ncRNA) transcripts in the cell with important
roles in modulation of different mechanisms. ANRIL is a long ncRNA with 3.8 kb length that …
roles in modulation of different mechanisms. ANRIL is a long ncRNA with 3.8 kb length that …