All for one and one for all: Mental disorders in one dimension

A Caspi, TE Moffitt - American Journal of Psychiatry, 2018 - Am Psychiatric Assoc
In both child and adult psychiatry, empirical evidence has now accrued to suggest that a
single dimension is able to measure a person's liability to mental disorder, comorbidity …

Childhood and adolescent adversity and cardiometabolic outcomes: a scientific statement from the American Heart Association

SF Suglia, KC Koenen, R Boynton-Jarrett, PS Chan… - Circulation, 2018 - Am Heart Assoc
Adverse experiences in childhood and adolescence, defined as subjectively perceived
threats to the safety or security of the child's bodily integrity, family, or social structures, are …

Promoting youth mental health during the COVID-19 pandemic: A longitudinal study

ML Rosen, AM Rodman, SW Kasparek, M Mayes… - PloS one, 2021 - journals.plos.org
The COVID-19 pandemic has introduced novel stressors into the lives of youth. Identifying
factors that protect against the onset of psychopathology in the face of these stressors is …

Future directions in childhood adversity and youth psychopathology

KA McLaughlin - Future work in clinical child and adolescent …, 2018 - taylorfrancis.com
Despite long-standing interest in the influence of adverse early experiences on mental
health, systematic scientific inquiry into childhood adversity and developmental outcomes …

Childhood adversity and neural development: Deprivation and threat as distinct dimensions of early experience

KA McLaughlin, MA Sheridan, HK Lambert - Neuroscience & Biobehavioral …, 2014 - Elsevier
A growing body of research has examined the impact of childhood adversity on neural
structure and function. Advances in our understanding of the neurodevelopmental …

Subjective and objective experiences of childhood adversity: A meta‐analysis of their agreement and relationships with psychopathology

ER Francis, A Tsaligopoulou, SE Stock… - Journal of child …, 2023 - Wiley Online Library
Background Researchers use both subjective self‐report and objective measures, such as
official records, to investigate the impact of childhood adversity on psychopathology …

Is the HPA axis as target for depression outdated, or is there a new hope?

A Menke - Frontiers in psychiatry, 2019 - frontiersin.org
Major depressive disorder (MDD) is a very common stress-related mental disorder that
carries a huge burden for affected patients and the society. It is associated with a high …

Effects of the social environment and stress on glucocorticoid receptor gene methylation: a systematic review

G Turecki, MJ Meaney - Biological psychiatry, 2016 - Elsevier
The early-life social environment can induce stable changes that influence
neurodevelopment and mental health. Research focused on early-life adversity revealed …

Rethinking the measurement of adversity: Moving toward second-generation research on adverse childhood experiences

JP Mersky, CE Janczewski, J Topitzes - Child maltreatment, 2017 - journals.sagepub.com
Research on adverse childhood experiences (ACEs) has unified the study of interrelated
risks and generated insights into the origins of disorder and disease. Ten indicators of child …

The role of early life stress in adult psychiatric disorders: a systematic review according to childhood trauma subtypes

CP Carr, CMS Martins, AM Stingel… - The Journal of …, 2013 - journals.lww.com
Early life stress (ELS; sexual abuse, physical abuse, emotional abuse, physical neglect, and
emotional neglect) has been the focus of numerous studies. It has been associated with the …