[HTML][HTML] Biomaterials to enhance stem cell transplantation

BN Kharbikar, P Mohindra, TA Desai - Cell Stem Cell, 2022 - cell.com
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …

Supramolecular biomaterials

MJ Webber, EA Appel, EW Meijer, R Langer - Nature materials, 2016 - nature.com
Polymers, ceramics and metals have historically dominated the application of materials in
medicine. Yet rationally designed materials that exploit specific, directional, tunable and …

Peptide‐based supramolecular therapeutics for fighting major diseases

Z Wang, H Luo, H Wang, M **ao, H Jia… - Advanced Functional …, 2024 - Wiley Online Library
Peptide‐based supramolecular therapeutics (PST) refer to those theranostic nanomedicines
based on peptide or peptide derivatives self‐assembly that are constructed in vitro or in vivo …

Hippo pathway effector Yap promotes cardiac regeneration

M **n, Y Kim, LB Sutherland, M Murakami, X Qi… - Proceedings of the …, 2013 - pnas.org
The adult mammalian heart has limited potential for regeneration. Thus, after injury,
cardiomyocytes are permanently lost, and contractility is diminished. In contrast, the …

MiRNA‐sequence indicates that mesenchymal stem cells and exosomes have similar mechanism to enhance cardiac repair

L Shao, Y Zhang, B Lan, J Wang… - BioMed research …, 2017 - Wiley Online Library
Mesenchymal stem cells (MSCs) repair infarcted heart through paracrine mechanism. We
sought to compare the effectiveness of MSCs and MSC‐derived exosomes (MSC‐Exo) in …

[HTML][HTML] Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease

SH Ranganath, O Levy, MS Inamdar, JM Karp - Cell stem cell, 2012 - cell.com
The broad repertoire of secreted trophic and immunomodulatory cytokines produced by
mesenchymal stem cells (MSCs), generally referred to as the MSC secretome, has …

Physical cues of biomaterials guide stem cell differentiation fate

A Higuchi, QD Ling, Y Chang, ST Hsu… - Chemical …, 2013 - ACS Publications
Millions of people lose or damage their organs or tissues due to disease, birth defects, or
accidents each year. Stem cells, such as embryonic stem cells (ESCs), induced pluripotent …

Pretreatment of cardiac stem cells with exosomes derived from mesenchymal stem cells enhances myocardial repair

Z Zhang, J Yang, W Yan, Y Li, Z Shen… - Journal of the American …, 2016 - ahajournals.org
Background Exosomes derived from mesenchymal stem cells (MSC s) were proved to boost
cell proliferation and angiogenic potency. We explored whether cardiac stem cells (CSCs) …

An injectable conductive hydrogel encapsulating plasmid DNA-eNOs and ADSCs for treating myocardial infarction

W Wang, B Tan, J Chen, R Bao, X Zhang, S Liang… - Biomaterials, 2018 - Elsevier
Myocardial infarction (MI) leads to the mass death of cardiomyocytes accompanying with the
unfavorable alternation of microenvironment, a fibrosis scar deprived of electrical …

Cardiotoxicity of kinase inhibitors: the prediction and translation of preclinical models to clinical outcomes

T Force, KL Kolaja - Nature reviews Drug discovery, 2011 - nature.com
Targeted therapeutics, particularly those that inhibit the activity of protein kinases that are
mutated and/or overexpressed in cancer, have revolutionized the treatment of some cancers …