Recent findings provide evidence for a functional interplay between DNA replication and the
seemingly distinct areas of cancer, development and pluripotency. Protein complexes …

To ensure that the genetic material is accurately passed down to daughter cells during
mitosis, dividing cells must duplicate their chromosomes and centrosomes once and only …

Purpose Triple-negative breast cancer (TNBC) is an aggressive disease lacking specific
biomarkers to guide treatment decisions. We evaluated the combined prognostic impact of …

DNA replicates in a timely manner with each cell division. Multiple proteins and factors are
involved in the initiation of DNA replication including a dynamic interaction between Cdc10 …

During cortical development, coordination of proliferation and differentiation ensures the
timely generation of different neural progenitor lineages that will give rise to mature neurons …

Abnormal tumor vascularity is one of the typical features of hepatocellular carcinoma (HCC).
In this study, the significance of contrast‐enhanced intraoperative ultrasonography …

Molecular mechanisms governing maintenance, commitment, and differentiation of stem
cells are largely unexploited. Molecules involved in the regulation of multiple cellular …

Balancing stem cell self-renewal and initiation of lineage specification programs is essential
for the development and homeostasis of the hematopoietic system. We have specifically …

The proliferation-promoting effect of neuropeptide Y (NPY) always functions in low-serum-
cultured vascular smooth muscle cells (VSMCs), and the phenotypic switch of VSMCs is …

Geminin is an important regulator of proliferation and differentiation in metazoans, which
predominantly inhibits the DNA replication licensing factor Cdt1, preventing genome over …