Besides the physiological regulation of water, sodium, and potassium homeostasis,
aldosterone modulates several physiological and pathological processes in the …

Aldosterone exerts direct effects on the vascular system by inducing oxidative stress,
inflammation, hypertrophic remodeling, fibrosis, and endothelial dysfunction. Aldosterone …

The clinical characteristics and outcomes in patients with clinical aldosterone-producing
adenomas harboring KCNJ5 mutations with or without subclinical hypercortisolism remain …

There exists a great knowledge gap in terms of long-term effects of various surgical and
pharmacological treatments on outcomes among primary aldosteronism (PA) patients. Using …

Background/Purpose Even though the increasing clinical recognition of primary
aldosteronism (PA) as a public health issue, its heightened risk profiles and the availability …

Objective Long-term outcomes (especially mortality and/or major cardiovascular events
(MACE)) of the unilateral primary aldosteronism (uPA) patients who underwent medical or …

Vascular endothelium has important regulatory functions in the cardiovascular system and a
pivotal role in the maintenance of vascular health and metabolic homeostasis. It has long …

Primary aldosteronism (PA) is the most common secondary form of arterial hypertension,
with a particularly high prevalence among patients with resistant hypertension. Aldosterone …

Primary aldosteronism (PA) is characterized by excess production of aldosterone from the
adrenal glands and is the most common and treatable cause of secondary hypertension …

Primary aldosteronism (PA) is a common form of secondary hypertension and has significant
cardiovascular consequences. Mutated channelopathy due to the activation of calcium …