Extracellular matrix: an important regulator of cell functions and skeletal muscle development

W Zhang, Y Liu, H Zhang - Cell & bioscience, 2021 - Springer
Extracellular matrix (ECM) is a kind of connective tissue in the cell microenvironment, which
is of great significance to tissue development. ECM in muscle fiber niche consists of three …

Skeletal muscle extracellular matrix–what do we know about its composition, regulation, and physiological roles? A narrative review

R Csapo, M Gumpenberger, B Wessner - Frontiers in physiology, 2020 - frontiersin.org
Skeletal muscle represents the largest body-composition component in humans. In addition
to its primary function in the maintenance of upright posture and the production of …

[HTML][HTML] Mechanisms regulating muscle regeneration: insights into the interrelated and time-dependent phases of tissue healing

L Forcina, M Cosentino, A Musarò - Cells, 2020 - mdpi.com
Despite a massive body of knowledge which has been produced related to the mechanisms
guiding muscle regeneration, great interest still moves the scientific community toward the …

Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche

SC Schüler, Y Liu, S Dumontier… - Frontiers in Cell and …, 2022 - frontiersin.org
The extracellular matrix (ECM) is an interconnected macromolecular scaffold occupying the
space between cells. Amongst other functions, the ECM provides structural support to …

[HTML][HTML] Role of transforming growth factor-β in skeletal muscle fibrosis: a review

A Ismaeel, JS Kim, JS Kirk, RS Smith… - International journal of …, 2019 - mdpi.com
Transforming growth factor-beta (TGF-β) isoforms are cytokines involved in a variety of
cellular processes, including myofiber repair and regulation of connective tissue formation …

Alignment, cross linking, and beyond: a collagen architect's guide to the skeletal muscle extracellular matrix

RP Wohlgemuth, SE Brashear… - American Journal of …, 2023 - journals.physiology.org
The muscle extracellular matrix (ECM) forms a complex network of collagens, proteoglycans,
and other proteins that produce a favorable environment for muscle regeneration, protect the …

[HTML][HTML] Muscle contracture and passive mechanics in cerebral palsy

RL Lieber, J Fridén - Journal of applied physiology, 2019 - journals.physiology.org
Skeletal muscle contractures represent the permanent shortening of a muscle-tendon unit,
resulting in loss of elasticity and, in extreme cases, joint deformation. They may result from …

Regulation of fibrosis in muscular dystrophy

LR Smith, ER Barton - Matrix Biology, 2018 - Elsevier
The production of force and power are inherent properties of skeletal muscle, and regulated
by contractile proteins within muscle fibers. However, skeletal muscle integrity and function …

3D Printed Magneto‐Active Microfiber Scaffolds for Remote Stimulation and Guided Organization of 3D In Vitro Skeletal Muscle Models

G Cedillo‐Servin, O Dahri, J Meneses, J van Duijn… - Small, 2024 - Wiley Online Library
This work reports the rational design and fabrication of magneto‐active microfiber meshes
with controlled hexagonal microstructures via melt electrowriting (MEW) of a magnetized …

Passive stiffness of fibrotic skeletal muscle in mdx mice relates to collagen architecture

SE Brashear, RP Wohlgemuth… - The Journal of …, 2021 - Wiley Online Library
Key points The amount of fibrotic material in dystrophic mouse muscles relates to contractile
function, but not passive function. Collagen fibres in skeletal muscle are associated with …