Recent progress of supramolecular chemotherapy based on host–guest interactions

M Yan, S Wu, Y Wang, M Liang, M Wang… - Advanced …, 2024 - Wiley Online Library
Chemotherapy is widely recognized as an effective approach for treating cancer due to its
ability to eliminate cancer cells using chemotherapeutic drugs. However, traditional …

Pillararene-Inspired Macrocycles: From Extended Pillar[n]arenes to Geminiarenes

JR Wu, G Wu, YW Yang - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus Macrocyclic compounds have been the primary tools in supramolecular
chemistry since their establishment due to their innate functional features of molecular …

Supramolecular assemblies of organo-functionalised hybrid polyoxometalates: from functional building blocks to hierarchical nanomaterials

JM Cameron, G Guillemot, T Galambos… - Chemical Society …, 2022 - pubs.rsc.org
This review provides a comprehensive overview of recent advances in the supramolecular
organisation and hierarchical self-assembly of organo-functionalised hybrid …

Metal–organic framework (MOF)‐based drug/cargo delivery and cancer therapy

MX Wu, YW Yang - Advanced Materials, 2017 - Wiley Online Library
Metal–organic frameworks (MOFs)—an emerging class of hybrid porous materials built from
metal ions or clusters bridged by organic linkers—have attracted increasing attention in …

Host–Guest chemistry based on solid-state pillar [n] arenes

S Ohtani, K Kato, S Fa, T Ogoshi - Coordination Chemistry Reviews, 2022 - Elsevier
Pillar [n] arenes, which were first reported by our group in 2008, are a new type of pillar-
shaped host molecule in host–guest chemistry with versatile and unique host–guest …

Noncovalently bound and mechanically interlocked systems using pillar [n] arenes

K Kato, S Fa, S Ohtani, T Shi, AM Brouwer… - Chemical Society …, 2022 - pubs.rsc.org
Pillar [n] arenes are pillar-shaped macrocyclic compounds owing to the methylene bridges
linking the para-positions of the units. Owing to their unique pillar-shaped structures, these …

Drug delivery by supramolecular design

MJ Webber, R Langer - Chemical Society Reviews, 2017 - pubs.rsc.org
The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …

Surveying macrocyclic chemistry: from flexible crown ethers to rigid cyclophanes

Z Liu, SKM Nalluri, JF Stoddart - Chemical Society Reviews, 2017 - pubs.rsc.org
Macrocycles are molecular entities that display a combination of molecular recognition and
complexation properties with vital implications for host–guest/supramolecular chemistry …

Challenges and opportunities of functionalized cucurbiturils for biomedical applications

H Yin, Q Cheng, D Bardelang, R Wang - JACS Au, 2023 - ACS Publications
Cucurbit [n] uril (CB [n]) macrocycles (especially CB [5] to CB [8]) have shown exceptional
attributes since their discovery in 2000. Their stability, water solubility, responsiveness to …

Supramolecular chemotherapy based on host–guest molecular recognition: a novel strategy in the battle against cancer with a bright future

J Zhou, G Yu, F Huang - Chemical Society Reviews, 2017 - pubs.rsc.org
Chemotherapy is currently one of the most effective ways to treat cancer. However,
traditional chemotherapy faces several obstacles to clinical trials, such as poor …