Introduction During the last 4 decades, registration of patients with primary
immunodeficiencies (PID) has played an essential role in different aspects of these diseases …

Using whole-exome sequencing to examine the genetic causes of immune deficiency in 235
common variable immunodeficiency (CVID) patients seen in the United States (Mount Sinai …

Abstract The Human Phenotype Ontology (HPO, https://hpo. jax. org) was launched in 2008
to provide a comprehensive logical standard to describe and computationally analyze …

To the Editor: An epidemic of coronavirus SARS-CoV-2 has become the focus of scientific
attention. 1 The high infectivity of SARS-CoV-2 and rapid rise in the number of patients …

Background In mid-December 2020, Israel started a nationwide mass vaccination campaign
against coronavirus disease 2019 (COVID-19). In the first few weeks, medical personnel …

Deep phenoty** has been defined as the precise and comprehensive analysis of
phenotypic abnormalities in which the individual components of the phenotype are observed …

Although it is estimated that COVID-19 life-threatening conditions may be diagnosed in less
than 1: 1000 infected individuals below the age of 50, but the real impact of this pandemic …

Mass SARS-Cov-2 vaccination campaign represents the only strategy to defeat the global
pandemic we are facing. Immunocompromised patients represent a vulnerable population at …

Chronic granulomatous disease (CGD) is a primary immunodeficiency of phagocyte function
due to defective NADPH oxidase (phox). Compared with the common types of CYBB/gp91 …

Background Data on immune responses to SARS-CoV-2 in patients with Primary Antibody
Deficiencies (PAD) are limited to infected patients and to heterogeneous cohorts after …