Drug-targeting methodologies with applications: A review

C Kleinstreuer, Y Feng… - World Journal of Clinical …, 2014 - pmc.ncbi.nlm.nih.gov
Targeted drug delivery to solid tumors is a very active research area, focusing mainly on
improved drug formulation and associated best delivery methods/devices. Drug-targeting …

Lung deposition analyses of inhaled toxic aerosols in conventional and less harmful cigarette smoke: a review

C Kleinstreuer, Y Feng - … journal of environmental research and public …, 2013 - mdpi.com
Inhaled toxic aerosols of conventional cigarette smoke may impact not only the health of
smokers, but also those exposed to second-stream smoke, especially children. Thus, less …

[HTML][HTML] Prediction of airway deformation effect on pulmonary air-particle dynamics: A numerical study

J Zhao, Y Feng, K Koshiyama, H Wu - Physics of Fluids, 2021 - pubs.aip.org
Most existing whole lung models neglect the airway deformation kinematics and assume the
lung airways are static. However, neglecting the airway deformation effect on pulmonary air …

Computational transport, phase change and deposition analysis of inhaled multicomponent droplet–vapor mixtures in an idealized human upper lung model

Y Feng, C Kleinstreuer, N Castro, A Rostami - Journal of aerosol science, 2016 - Elsevier
Numerous inhalable aerosols consist of multiple nano-to-microscale solid or liquid particles
with dissolved or embedded compounds, as well as associated vapors. In general, of …

Lung aerosol dynamics of airborne influenza A virus-laden droplets and the resultant immune system responses: An in silico study

A Haghnegahdar, J Zhao, Y Feng - Journal of aerosol science, 2019 - Elsevier
Abstract Influenza A Virus (IAV) replications start from the deposition of inhaled virus-laden
droplets on the epithelial cells in the pulmonary tracts. In order to understand the local …

[HTML][HTML] Cytotoxic evaluation of e-liquid aerosol using different lung-derived cell models

S Scheffler, H Dieken, O Krischenowski… - International Journal of …, 2015 - mdpi.com
The in vitro toxicological evaluation of e-liquid aerosol is an important aspect of consumer
protection, but the cell model is of great significance. Due to its water solubility, e-liquid …

The customizable E-cigarette resistance influences toxicological outcomes: Lung degeneration, inflammation, and oxidative stress-induced in a rat model

S Cirillo, F Vivarelli, E Turrini, C Fimognari… - Toxicological …, 2019 - academic.oup.com
Despite the knowledge gap regarding the risk-benefit ratio of the electronic cigarette (e-cig),
its use has grown exponentially, even in teenagers. E-cig vapor contains carcinogenic …