Amino acids are the building blocks of protein synthesis. They are structural elements and
energy sources of cells necessary for normal cell growth, differentiation and function. Amino …

Glioblastoma (GBM) is the most deadly type of malignant brain tumor, despite extensive
molecular analyses of GBM cells. In recent years, the tumor microenvironment (TME) has …

Cancer cells rewire metabolism to favour the generation of specialized metabolites that
support tumour growth and reshape the tumour microenvironment,. Lysine functions as a …

As one of the four major means of cancer treatment including surgery, radiotherapy (RT),
chemotherapy, immunotherapy, RT can be applied to various cancers as both a radical …

Importance The gut microbiome, home to the vast kingdom of diverse commensal bacteria
and other microorganisms residing within the gut, was once thought to only have roles …

Tumor metabolism is emerging as a potential target for cancer therapies. This new approach
holds particular promise for the treatment of glioblastoma, a highly lethal brain tumor that is …

Immunotherapy is regarded as one of the most promising approaches for treating tumors,
with a multitude of immunotherapeutic thoughts currently under consideration for the lethal …

Glioblastoma (GBM) is the most aggressive and lethal form of brain tumor in human adults.
Myeloid-lineage cells, including macrophages, microglia, myeloid-derived suppressor cells …

Simple Summary The most prevalent and lethal primary brain tumor, glioblastoma
multiforme (GBM), exhibits fast growth and widespread invasion and has a poor prognosis …

Evidence is accumulating that the tumour microenvironment (TME) has a key role in the
progression of gliomas. Non-neoplastic cells in addition to the tumour cells are therefore …