Glial-restricted progenitor cells: a cure for diseased brain?

P Rogujski, B Lukomska, M Janowski… - Biological …, 2024 - SciELO Chile
The central nervous system (CNS) is home to neuronal and glial cells. Traditionally, glia was
disregarded as just the structural support across the brain and spinal cord, in striking …

Myelin sheath injury and repairment after subarachnoid hemorrhage

M Chen, P Guo, X Ru, Y Chen, S Zuo… - Frontiers in …, 2023 - frontiersin.org
Subarachnoid hemorrhage (SAH) can lead to damage to the myelin sheath in white matter.
Through classification and analysis of relevant research results, the discussion in this paper …

Time-course pattern of neuronal loss and gliosis in gerbil hippocampi following mild, severe, or lethal transient global cerebral ischemia

TK Lee, H Kim, M Song, JC Lee, JH Park… - Neural Regeneration …, 2019 - journals.lww.com
Transient ischemia in the whole brain leads to neuronal loss/death in vulnerable brain
regions. The striatum, neocortex and hippocampus selectively loose specific neurons after …

Neuregulin-1/PI3K signaling effects on oligodendrocyte proliferation, remyelination and behaviors deficit in a male mouse model of ischemic stroke

MY Cui, YQ Fu, ZL Li, Y Zheng, Y Yu, C Zhang… - Experimental …, 2023 - Elsevier
In this study, we investigated the effect of neuregulin-1 (NRG1) on demyelination and
neurological function in an ischemic stroke model, and further explored its neuroprotective …

Ischemia-Induced Cognitive Impairment Is Improved via Remyelination and Restoration of Synaptic Density in the Hippocampus after Treatment with COG-Up® in a …

TK Lee, J Hong, JW Lee, SS Kim, H Sim, JC Lee… - Veterinary …, 2021 - mdpi.com
Cerebrovascular disease such as ischemic stroke develops cognitive impairment due to
brain tissue damage including neural loss, demyelination and decrease in synaptic density …

Ethnicity-Dependent Effects of Schizophrenia Risk Variants of the OLIG2 Gene on OLIG2 Transcription and White Matter Integrity

H Komatsu, H Takeuchi, Y Kikuchi, C Ono… - Schizophrenia …, 2020 - academic.oup.com
Previous studies have indicated associations between several OLIG2 gene single-
nucleotide polymorphisms (SNPs) and susceptibility to schizophrenia among Caucasians …

Alleviating early demyelination in ischaemia/reperfusion by inhibiting sphingosine‐1‐phosphate receptor 2 could protect visual function from impairment

J Xue, J Lin, Z Liu, Q Zhang, J Tang, J Han… - Brain …, 2023 - Wiley Online Library
Retinal ischaemia/reperfusion (I/R) injury is a common cause of retinal ganglion cell (RGC)
apoptosis and axonal degeneration, resulting in irreversible visual impairment. However …

Role of MEK partner-1 in cancer stemness through MEK/ERK pathway in cancerous neural stem cells, expressing EGFRviii

SJ Kwon, OS Kwon, KT Kim, YH Go, S Yu, B Lee… - Molecular cancer, 2017 - Springer
Abstract Background Glioma stem cells (GSCs) are a major cause of the frequent relapse
observed in glioma, due to their high drug resistance and their differentiation potential …

Pathophysiology of ganglioside GM1 in ischemic stroke: ganglioside GM1: a critical review

W Zhang, PR Krafft, T Wang, JH Zhang… - Cell …, 2019 - journals.sagepub.com
Ganglioside GM1 is a member of the ganglioside family which has been used in many
countries and is thought of as a promising alternative treatment for preventing several …

Changes of myelin basic protein in the hippocampus of an animal model of type 2 diabetes

SM Nam, HJ Kwon, W Kim, JW Kim, KR Hahn… - Laboratory Animal …, 2018 - Springer
In this study, we observed chronological changes in the immunoreactivity and expression
level of myelin basic protein (MBP), one of the most abundant proteins in the central nervous …