The perilipin family of lipid droplet proteins: Gatekeepers of intracellular lipolysis

C Sztalryd, DL Brasaemle - Biochimica et biophysica acta (bba)-molecular …, 2017 - Elsevier
Lipid droplets in chordates are decorated by two or more members of the perilipin family of
lipid droplet surface proteins. The perilipins sequester lipids by protecting lipid droplets from …

Biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites

A Pol, SP Gross, RG Parton - Journal of Cell Biology, 2014 - rupress.org
Lipid droplets (LDs) are ubiquitous dynamic organelles that store and supply lipids in all
eukaryotic and some prokaryotic cells for energy metabolism, membrane synthesis, and …

Lipid droplets in health and disease

G Onal, O Kutlu, D Gozuacik… - Lipids in health and …, 2017 - Springer
Lipids are essential building blocks synthesized by complex molecular pathways and
deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found …

Lipid droplet biogenesis

F Wilfling, JT Haas, TC Walther, RV Farese Jr - Current opinion in cell …, 2014 - Elsevier
Lipid droplets (LDs) are found in most cells, where they play central roles in energy and
membrane lipid metabolism. The de novo biogenesis of LDs is a fascinating, yet poorly …

The assembly of lipid droplets and their roles in challenged cells

WM Henne, ML Reese, JM Goodman - The EMBO journal, 2018 - embopress.org
Cytoplasmic lipid droplets are important organelles in nearly every eukaryotic and some
prokaryotic cells. Storing and providing energy is their main function, but they do not work in …

A conserved family of proteins facilitates nascent lipid droplet budding from the ER

V Choudhary, N Ojha, A Golden, WA Prinz - Journal of Cell Biology, 2015 - rupress.org
Lipid droplets (LDs) are found in all cells and play critical roles in lipid metabolism. De novo
LD biogenesis occurs in the endoplasmic reticulum (ER) but is not well understood. We …

The lipid droplet—a well-connected organelle

Q Gao, JM Goodman - Frontiers in cell and developmental biology, 2015 - frontiersin.org
Our knowledge of inter-organellar communication has grown exponentially in recent years.
This review focuses on the interactions that cytoplasmic lipid droplets have with other …

[HTML][HTML] Emerging roles for conjugated sterols in plants

A Ferrer, T Altabella, M Arró, A Boronat - Progress in lipid research, 2017 - Elsevier
In plants, sterols are found in free form (free sterols, FSs) and conjugated as steryl esters
(SEs), steryl glycosides (SGs) and acyl steryl glycosides (ASGs). Conjugated sterols are …

Lipid droplets as immune modulators in myeloid cells

MH den Brok, TK Raaijmakers, E Collado-Camps… - Trends in …, 2018 - cell.com
Lipid droplets (LDs) were initially described as fat storage organelles in adipocytes, but are
increasingly recognized as dynamic players in lipid metabolism, with important roles not …

Architecture of lipid droplets in endoplasmic reticulum is determined by phospholipid intrinsic curvature

V Choudhary, G Golani, AS Joshi, S Cottier… - Current Biology, 2018 - cell.com
Lipid droplets (LDs) store fats and play critical roles in lipid and energy homeostasis. They
form between the leaflets of the endoplasmic reticulum (ER) membrane and consist of a …