Objective: To revise the “Clinical Practice Guidelines for the Sustained Use of Sedatives and
Analgesics in the Critically Ill Adult” published in Critical Care Medicine in 2002. Methods …

Remimazolam (CNS7056) is a novel benzodiazepine for intravenous sedation; it has an
ultra-short duration of action and was recently approved for use in procedural sedation and …

The American College of Critical Care Medicine (ACCM), which honors individuals for their
achievements and contributions to multidisciplinary critical care medicine, is the consultative …

Study objective To determine whether the use of continuous IV sedation is associated with
prolongation of the duration of mechanical ventilation. Design Prospective observational …

Objective: To compare a practice of protocol-directed sedation during mechanical ventilation
implemented by nurses with traditional non-protocol-directed sedation administration …

Importance Alternatives to sedative medications, such as music, may alleviate the anxiety
associated with ventilatory support. Objective To test whether listening to self-initiated …

Delirium can be defined as an 'acute brain dysfunction.'Compared to dementia, which is a
disease that deteriorates the brain function chronically, delirium shows very similar …

Objective: To compare dexmedetomidine-based to propofol-based sedation after coronary
artery bypass graft (CABG) surgery in the intensive care unit (ICU). Design: Randomized …

Effective use of sedative-hypnotic and analgesic agents is an integral part of providing
patient comfort and safety. Of the numerous drugs administered, benzodiazepines, propofol …

Patients who are critically ill and on mechanical ventilation frequently require sedation and
analgesic therapy to optimize patient comfort, facilitate patient-ventilator synchrony, and …