Due to the high compressibility of the gas core compared with the surrounding liquid
medium, microbubbles are highly responsive to ultrasound excitation and exhibit robust …

Sonoporation is the process of transient pore formation in the cell membrane triggered by
ultrasound (US). Numerous studies have provided us with firm evidence that sonoporation …

Background The primary aim of our study was to evaluate the safety and potential toxicity of
gemcitabine combined with microbubbles under sonication in inoperable pancreatic cancer …

Purpose: The purpose of this study was to investigate the ability and efficacy of inducing
sonoporation in a clinical setting, using commercially available technology, to increase the …

Ultrasound induced microbubble cavitation can cause enhanced permeability across natural
barriers of tumors such as vessel walls or cellular membranes, allowing for enhanced …

Many diseases and conditions affect a relatively localized area of the body. They can be
treated either by direct deposition of drug in the target area, or by giving the drug …

Purpose Adenocarcinoma of the pancreas remains one of the most lethal human cancers.
The high mortality rates associated with this form of cancer are subsequent to late-stage …

Background Ultrasound-targeted microbubble destruction (UTMD) is a type of ultrasound
therapy, in which low frequency moderate power ultrasound is combined with microbubbles …

Having first been developed for ultrasound imaging, nowadays, microbubbles are proposed
as tools for ultrasound-assisted gene delivery, too. Their behavior during ultrasound …

The use of ultrasound (US) and microbubbles (MB), usually referred to as sonoporation, has
great potential to increase the efficacy of chemotherapy. However, the molecular …