Skeletal muscle is one of the main regulators of carbohydrate and lipid metabolism in our
organism, and therefore, it is highly susceptible to changes in glucose and fatty acid (FA) …

Intramyocellular lipid (IMCL) is predominantly stored as intramuscular triglyceride (IMTG) in
lipid droplets and is utilized as metabolic fuel during physical exercise. IMTG is also …

Key point Optimal vascular function is critical for health, and endurance training (ET) has
previously been shown to be an effective method of improving this. Sprint interval training …

For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

Key points Increases in aerobic capacity and intramuscular triglyceride (IMTG) utilization are
well‐described adaptations to endurance training (ET) and contribute to improvements in …

Lipid droplet (LD) formation is a hallmark of cellular stress. Cells attempt to combat noxious
stimuli by switching their metabolism from oxidative phosphorylation to glycolysis, sparing …

In-vivo and in-vitro data suggest that Plin5 is part of a cell-adaptive response to high lipid
oxidative metabolism to protect lipid droplet storage against neutral lipases and, so, limit …

Evidence indicates that skeletal muscle lipid droplet-associated proteins (PLINs) regulate
lipolysis through protein-protein interactions on the lipid droplet surface. In adipocytes …

The discovery of perilipin (PLIN) 1 provided a major conceptual shift in the understanding of
adipose tissue lipolysis and generated intense interest in lipid droplet biology research. The …

The lipid droplet (LD)-associated protein adipose differentiation-related protein (ADRP or
PLIN2) is required for the formation and stability of the LD organelle, whereas its biological …