Immune targets for therapeutic development in depression: towards precision medicine

WC Drevets, GM Wittenberg, ET Bullmore… - Nature reviews Drug …, 2022 - nature.com
Over the past two decades, compelling evidence has emerged indicating that immune
mechanisms can contribute to the pathogenesis of major depressive disorder (MDD) and …

Stress to inflammation and anhedonia: Mechanistic insights from preclinical and clinical models

CC Boyle, JE Bower, NI Eisenberger… - … & Biobehavioral Reviews, 2023 - Elsevier
Anhedonia, as evidenced by impaired pleasurable response to reward, reduced reward
motivation, and/or deficits in reward-related learning, is a common feature of depression …

A corticoamygdalar pathway controls reward devaluation and depression using dynamic inhibition code

Z Yuan, Z Qi, R Wang, Y Cui, S An, G Wu, Q Feng… - Neuron, 2023 - cell.com
Reward devaluation adaptively controls reward intake. It remains unclear how cortical
circuits causally encode reward devaluation in healthy and depressed states. Here, we …

How handling extreme C-reactive protein (CRP) values and regularization influences CRP and depression criteria associations in network analyses

DP Moriarity, SR Horn, MM Kautz, JMB Haslbeck… - Brain, Behavior, and …, 2021 - Elsevier
Increasingly, it has been recognized that analysis at the symptom, rather than diagnostic,
level will drive progress in the field of immunopsychiatry. Network analysis offers a useful …

Assessing food-evoked emotions using functional magnetic resonance imaging: A systematic review

L Luo, P Han - Food Quality and Preference, 2023 - Elsevier
Research on food-related emotions has increased over the decades. Advances in functional
magnetic resonance imaging (fMRI) have made it possible to investigate the neural …

Characterizing eating behavioral phenotypes in mood disorders: a narrative review

E Koning, J Vorstman, RS McIntyre… - Psychological …, 2022 - cambridge.org
Mood disorders, including depressive and bipolar disorders, represent a multidimensional
and prevalent group of psychiatric illnesses characterized by disturbances in emotion …

Use of transcutaneous auricular vagus nerve stimulation as an adjuvant therapy for the depressive symptoms of COVID-19: A literature review

ZP Guo, P Sörös, ZQ Zhang, MH Yang, D Liao… - Frontiers in …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19) comprises more than just severe acute
respiratory syndrome. It also interacts with the cardiovascular, nervous, renal, and immune …

Controversies in the pharmacotherapy of adolescent depression

G Masi - Current pharmaceutical design, 2022 - benthamdirect.com
Background: Although fluoxetine and, in the USA, escitalopram are approved for depression
in adolescence, substantial concern surrounds antidepressant use in youth. Major …

Unveiling the interoception impairment in various major depressive disorder stages

H Zhou, J Liu, Y Wu, Z Huang, W Wang… - CNS Neuroscience …, 2024 - Wiley Online Library
Background The intricate pathophysiological mechanisms of major depressive disorder
(MDD) necessitate the development of comprehensive early indicators that reflect the …

A study on the effects of metacinnabar (β-HgS) on weight and appetite recovery in stressed mice

Y Qiao, H Chen, J Guo, X Zhang, X Liang, L Wei… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Depression is a prevalent stress disorder, yet the
underlying physiological mechanisms linking stress to appetite and weight loss remain …