Compartmentation is essential for the localization of biological processes within a cell. In
2010, three groups independently reported that cytidine triphosphate synthase (CTPS), a …

The development of fluorescent labels and powerful imaging technologies in the last two
decades has revolutionized the field of fluorescence microscopy, which is now widely used …

Introduction In vivo imaging provides a window into the spatially complex, rapidly evolving
physiology of the cell that structural imaging alone cannot. However, observing this …

The animal foregut is the first tissue to encounter ingested food, bacteria, and viruses. We
characterized the adult Drosophila foregut using transcriptomics to better understand how it …

Here, we document a collection of∼ 7434 MiMIC (Minos Mediated Integration Cassette)
insertions of which 2854 are inserted in coding introns. They allowed us to create a library of …

The Drosophila genome contains> 13000 protein-coding genes, the majority of which
remain poorly investigated. Important reasons include the lack of antibodies or reporter …

We demonstrate the versatility of a collection of insertions of the transposon Minos-mediated
integration cassette (MiMIC), in Drosophila melanogaster. MiMIC contains a gene-trap …

The use of genetic mutations to study protein functions in vivo is a central paradigm of
modern biology. Recent advances in reverse genetics such as RNA interference and …

Neuronal information processing requires a large amount of energy, indicating that sugars
and other metabolites must be efficiently delivered. However, reliable neuronal function also …

Throughout life, adult organs continually adapt to variable environmental factors. Adaptive
mechanisms must fundamentally differ from homeostatic maintenance, but little is known …