The shelterin protein expansion of telomere dynamics: Linking early life adversity, life history, and the hallmarks of aging

SE Wolf, I Shalev - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Aging is characterized by functional decline occurring alongside changes to several
hallmarks of aging. One of the hallmarks includes attrition of repeated DNA sequences …

Telomeres in ecology and evolution: A review and classification of hypotheses

M Tobler, D Gómez‐Blanco, A Hegemann… - Molecular …, 2022 - Wiley Online Library
Research on telomeres in the fields of ecology and evolution has been rapidly expanding
over the last two decades. This has resulted in the formulation of a multitude of, often name …

Increased glucocorticoid concentrations in early life cause mitochondrial inefficiency and short telomeres

S Casagrande, A Stier, P Monaghan… - Journal of …, 2020 - journals.biologists.com
Telomeres are DNA structures that protect chromosome ends. However, telomeres shorten
during cell replication and at critically low lengths can reduce cell replicative potential …

Longer telomeres during early life predict higher lifetime reproductive success in females but not males

BJ Heidinger, AC Kucera… - Proceedings of the …, 2021 - royalsocietypublishing.org
The mechanisms that contribute to variation in lifetime reproductive success are not well
understood. One possibility is that telomeres, conserved DNA sequences at chromosome …

Lizards from warm and declining populations are born with extremely short telomeres

A Dupoué, P Blaimont, F Angelier… - Proceedings of the …, 2022 - National Acad Sciences
Aging is the price to pay for acquiring and processing energy through cellular activity and life
history productivity. Climate warming can exacerbate the inherent pace of aging, as …

Of telomeres and temperature: measuring thermal effects on telomeres in ectothermic animals

CR Friesen, E Wapstra, M Olsson - Molecular ecology, 2022 - Wiley Online Library
Ectotherms are classic models for understanding life‐history tradeoffs, including the
reproduction–somatic maintenance tradeoffs that may be reflected in telomere length and …

Longitudinal telomere dynamics within natural lifespans of a wild bird

ML Pepke, T Kvalnes, J Wright, YG Araya-Ajoy… - Scientific Reports, 2023 - nature.com
Telomeres, the nucleotide sequences that protect the ends of eukaryotic chromosomes,
shorten with each cell division and telomere loss may be influenced by environmental …

Functional responses in a lizard along a 3.5‐km altitudinal gradient

N Serén, R Megía‐Palma, T Simčič… - Journal of …, 2023 - Wiley Online Library
Aim Physiological and metabolic performance are key mediators of the functional response
of species to environmental change. Few environments offer such a multifaceted array of …

Telomere length positively correlates with pace‐of‐life in a sex‐and cohort‐specific way and elongates with age in a wild mammal

ML Tissier, P Bergeron, D Garant, S Zahn… - Molecular …, 2022 - Wiley Online Library
Understanding ageing and the diversity of life histories is a cornerstone in biology.
Telomeres, the protecting caps of chromosomes, are thought to be involved in ageing …

Accelerated aging in serious mental disorders

FS Bersani, SH Mellon, VI Reus… - Current Opinion in …, 2019 - journals.lww.com
We define and discuss several proposed biological aging markers that have been examined
in SMDs, we review the most recent findings, and we conclude with opinions regarding the …