Plasmodium falciparum causes the most severe and fatal form of malaria in humans with
over half a million deaths each year. Cerebral malaria, a complex neurological syndrome of …

For Plasmodium falciparum, the most widespread and virulent malaria parasite that infects
humans, persistence depends on continuous asexual replication in red blood cells, while …

Plasmodium falciparum remains the deadliest parasite species in the world, responsible for
229 million cases of human malaria in 2019. The ability of the P. falciparum parasite to …

Background Malaria pathogenesis relies on sexual gametocyte forms of the malaria parasite
to be transmitted between the infected human and the mosquito host but the molecular …

The epigenome of the malaria parasite, Plasmodium falciparum, is associated with
regulation of various essential processes in the parasite including control of proliferation …

Differentiation from asexual blood stages to mature sexual gametocytes is required for the
transmission of malaria parasites. Here, we report that the ApiAP2 transcription factor, PfAP2 …

Gene expression in Plasmodia integrates post-transcriptional regulation with epigenetic
marking of active genomic regions through histone post-translational modifications (PTMs) …

Dynamic control of gene expression is critical for blood stage development of malaria
parasites. Here, we used multi-omic analyses to investigate transcriptional regulation by the …

Human malaria is a devastating disease and a major cause of poverty in resource-limited
countries. To develop and adapt within hosts Plasmodium falciparum undergoes drastic …

Abstract Background The malaria parasite Plasmodium falciparum has an unusually
euchromatic genome with poorly conserved positioning of nucleosomes in intergenic …