Technology of deep brain stimulation: current status and future directions

JK Krauss, N Lipsman, T Aziz, A Boutet… - Nature Reviews …, 2021 - nature.com
Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

[HTML][HTML] Advances in technical aspects of deep brain stimulation surgery

M Schulder, A Mishra, A Mammis, A Horn… - Stereotactic and …, 2023 - karger.com
Background: Deep brain stimulation has become an established technology for the
treatment of patients with a wide variety of conditions, including movement disorders …

[HTML][HTML] Lead-DBS v3. 0: Map** deep brain stimulation effects to local anatomy and global networks

C Neudorfer, K Butenko, S Oxenford, N Rajamani… - Neuroimage, 2023 - Elsevier
Following its introduction in 2014 and with support of a broad international community, the
open-source toolbox Lead-DBS has evolved into a comprehensive neuroimaging platform …

Predicting optimal deep brain stimulation parameters for Parkinson's disease using functional MRI and machine learning

A Boutet, R Madhavan, GJB Elias, SE Joel… - Nature …, 2021 - nature.com
Commonly used for Parkinson's disease (PD), deep brain stimulation (DBS) produces
marked clinical benefits when optimized. However, assessing the large number of possible …

Neural signatures of indirect pathway activity during subthalamic stimulation in Parkinson's disease

LA Steiner, D Crompton, S Sumarac, A Vetkas… - Nature …, 2024 - nature.com
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) produces an
electrophysiological signature called evoked resonant neural activity (ERNA); a high …

Optimal deep brain stimulation sites and networks for cervical vs. generalized dystonia

A Horn, MM Reich, S Ewert, N Li, B Al-Fatly… - Proceedings of the …, 2022 - pnas.org
Dystonia is a debilitating disease with few treatment options. One effective option is deep
brain stimulation (DBS) to the internal pallidum. While cervical and generalized forms of …

[HTML][HTML] Spectral and spatial distribution of subthalamic beta peak activity in Parkinson's disease patients

N Darcy, R Lofredi, B Al-Fatly, WJ Neumann… - Experimental …, 2022 - Elsevier
Current efforts to optimise subthalamic deep brain stimulation in Parkinson's disease
patients aim to harness local oscillatory activity in the beta frequency range (13–35 Hz) as a …

Probabilistic map** of deep brain stimulation: insights from 15 years of therapy

GJB Elias, A Boutet, SE Joel, J Germann… - Annals of …, 2021 - Wiley Online Library
Deep brain stimulation (DBS) depends on precise delivery of electrical current to target
tissues. However, the specific brain structures responsible for best outcome are still debated …

Past, present, and future of deep brain stimulation: hardware, software, imaging, physiology and novel approaches

J Frey, J Cagle, KA Johnson, JK Wong… - Frontiers in …, 2022 - frontiersin.org
Deep brain stimulation (DBS) has advanced treatment options for a variety of neurologic and
neuropsychiatric conditions. As the technology for DBS continues to progress, treatment …

[HTML][HTML] Deep brain stimulation: Imaging on a group level

S Treu, B Strange, S Oxenford, WJ Neumann, A Kühn… - Neuroimage, 2020 - Elsevier
Abstract Deep Brain Stimulation (DBS) is an established treatment option for movement
disorders and is under investigation for treatment in a growing number of other brain …