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Gene drive and symbiont technologies for control of mosquito-borne diseases
Mosquito-borne diseases, such as dengue and malaria, pose a significant burden to global
health. Current control strategies with insecticides are only moderately effective. Scalable …
health. Current control strategies with insecticides are only moderately effective. Scalable …
Wolbachia-based strategies for control of agricultural pests
JT Gong, TP Li, MK Wang, XY Hong - Current Opinion in Insect Science, 2023 - Elsevier
Highlights•Wolbachia-based incompatible insect technique (IIT) is effective for mosquito-
borne diseases.•Wolbachia-based approaches are proposed for the protection of plants …
borne diseases.•Wolbachia-based approaches are proposed for the protection of plants …
Reduced dengue incidence following city-wide wMel Wolbachia mosquito releases throughout three Colombian cities: Interrupted time series analysis and a …
ID Velez, SK Tanamas, MP Arbelaez… - PLoS Neglected …, 2023 - journals.plos.org
Background The introduction of Wolbachia (w Mel strain) into Aedes aegypti mosquitoes
reduces their capacity to transmit dengue and other arboviruses. Randomised and non …
reduces their capacity to transmit dengue and other arboviruses. Randomised and non …
Low-input PacBio sequencing generates high-quality individual fly genomes and characterizes mutational processes
Long-read sequencing, exemplified by PacBio, revolutionizes genomics, overcoming
challenges like repetitive sequences. However, the high DNA requirement (> 1 µg) is …
challenges like repetitive sequences. However, the high DNA requirement (> 1 µg) is …
Field deployment of Wolbachia-infected Aedes aegypti using uncrewed aerial vehicle
YH Lin, DA Joubert, S Kaeser, C Dowd, J Germann… - Science Robotics, 2024 - science.org
Over the past 50 years, there has been a marked increase in diseases like dengue fever,
chikungunya, and Zika. The World Mosquito Program (WMP) has developed an approach …
chikungunya, and Zika. The World Mosquito Program (WMP) has developed an approach …
An economic evaluation of Wolbachia deployments for dengue control in Vietnam
HC Turner, DL Quyen, R Dias, PT Huong… - PLOS Neglected …, 2023 - journals.plos.org
Introduction Dengue is a major public health challenge and a growing problem due to
climate change. The release of Aedes aegypti mosquitoes infected with the intracellular …
climate change. The release of Aedes aegypti mosquitoes infected with the intracellular …
Wolbachia ‐carrying Aedes mosquitoes for preventing dengue infection
T Fox, Y Sguassero, M Chaplin, W Rose… - Cochrane Database …, 2024 - cochranelibrary.com
Background Dengue is a global health problem of high significance, with 3.9 billion people
at risk of infection. The geographic expansion of dengue virus (DENV) infection has resulted …
at risk of infection. The geographic expansion of dengue virus (DENV) infection has resulted …
Wolbachia wAlbB remains stable in Aedes aegypti over 15 years but exhibits genetic background-dependent variation in virus blocking
X Liang, CH Tan, Q Sun, M Zhang, PSJ Wong… - PNAS …, 2022 - academic.oup.com
The ability of the maternally transmitted endosymbiotic bacterium Wolbachia to induce
cytoplasmic incompatibility (CI) and virus blocking makes it a promising weapon for …
cytoplasmic incompatibility (CI) and virus blocking makes it a promising weapon for …
wMel replacement of dengue-competent mosquitoes is robust to near-term climate change
Rising temperatures are impacting the range and prevalence of mosquito-borne diseases. A
promising biocontrol technology replaces wild mosquitoes with those carrying the virus …
promising biocontrol technology replaces wild mosquitoes with those carrying the virus …
[HTML][HTML] Culex-Transmitted Diseases: Mechanisms, Impact, and Future Control Strategies using Wolbachia
Mosquitoes of the Culex genus are responsible for a large burden of zoonotic virus
transmission globally. Collectively, they play a significant role in the transmission of …
transmission globally. Collectively, they play a significant role in the transmission of …