Genetics of structural and functional brain changes in autism spectrum disorder
Autism spectrum disorder (ASD) is a neurological and developmental disorder characterized
by social impairment and restricted interactive and communicative behaviors. It may occur …
by social impairment and restricted interactive and communicative behaviors. It may occur …
Neuroimaging genetics approaches to identify new biomarkers for the early diagnosis of autism spectrum disorder
Autism-spectrum disorders (ASDs) are developmental disabilities that manifest in early
childhood and are characterized by qualitative abnormalities in social behaviors …
childhood and are characterized by qualitative abnormalities in social behaviors …
Roles of the oxytocin receptor (OXTR) in human diseases
K Pierzynowska, L Gaffke, M Żabińska, Z Cyske… - International journal of …, 2023 - mdpi.com
The oxytocin receptor (OXTR), encoded by the OXTR gene, is responsible for the signal
transduction after binding its ligand, oxytocin. Although this signaling is primarily involved in …
transduction after binding its ligand, oxytocin. Although this signaling is primarily involved in …
Oxytocin receptor gene (OXTR) polymorphisms and social, emotional and behavioral functioning in children and adolescents: A systematic narrative review
This study systematically reviewed available evidence regarding associations between
polymorphisms of the oxytocin receptor (OXTR) gene and socio-emotional and behavioral …
polymorphisms of the oxytocin receptor (OXTR) gene and socio-emotional and behavioral …
A systematic review of common genetic variation and biological pathways in autism spectrum disorder
DA Rodriguez-Gomez, DP Garcia-Guaqueta… - BMC neuroscience, 2021 - Springer
Background Autism spectrum disorder (ASD) is a complex neurodevelopmental condition
characterized by persistent deficits in social communication and interaction. Common …
characterized by persistent deficits in social communication and interaction. Common …
[HTML][HTML] Epigenetic variability in the human oxytocin receptor (OXTR) gene: A possible pathway from early life experiences to psychopathologies
The human oxytocin (OXT) system is implicated in the regulation of complex social
behaviors, as well as in psychopathologies characterized by social deficits. Emerging …
behaviors, as well as in psychopathologies characterized by social deficits. Emerging …
[HTML][HTML] Acute IL-6 exposure triggers canonical IL6Ra signaling in hiPSC microglia, but not neural progenitor cells
ACM Couch, S Solomon, RRR Duarte… - Brain, Behavior, and …, 2023 - Elsevier
Background Prenatal exposure to elevated interleukin (IL)-6 levels is associated with
increased risk for psychiatric disorders with a putative neurodevelopmental origin, such as …
increased risk for psychiatric disorders with a putative neurodevelopmental origin, such as …
Oxytocin receptor gene (OXTR) DNA methylation is associated with autism and related social traits–A systematic review
There is emerging evidence implicating oxytocin receptor gene (OXTR) DNA methylation
(DNAm) in social behaviour. This review investigated its association with autism spectrum …
(DNAm) in social behaviour. This review investigated its association with autism spectrum …
Gut microbiota metabolites in autistic children: An epigenetic perspective
Gut microbiota has become an issue of great importance recently due to its major role in
autism spectrum disorder (ASD). Over the past three decades, there has been a sustained …
autism spectrum disorder (ASD). Over the past three decades, there has been a sustained …
Synthesis of genetic association studies on autism spectrum disorders using a genetic model-free approach
I Mpoulimari, E Zintzaras - Psychiatric genetics, 2022 - journals.lww.com
Background Autism spectrum disorder (ASD) is a clinically and genetically heterogeneous
group of neurodevelopmental disorders. Despite the extensive efforts of scientists, the …
group of neurodevelopmental disorders. Despite the extensive efforts of scientists, the …