Omics-based strategies in precision medicine: toward a paradigm shift in inborn errors of metabolism investigations
The rise of technologies that simultaneously measure thousands of data points represents
the heart of systems biology. These technologies have had a huge impact on the discovery …
the heart of systems biology. These technologies have had a huge impact on the discovery …
A review of metabolomics approaches and their application in identifying causal pathways of childhood asthma
KN Turi, L Romick-Rosendale, KK Ryckman… - Journal of Allergy and …, 2018 - Elsevier
Because asthma is a disease that results from host-environment interactions, an approach
that allows assessment of the effect of the environment on the host is needed to understand …
that allows assessment of the effect of the environment on the host is needed to understand …
COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms
We need to effectively combine the knowledge from surging literature with complex datasets
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …
Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms
The development of computational approaches in systems biology has reached a state of
maturity that allows their transition to systems medicine. Despite this progress, intuitive …
maturity that allows their transition to systems medicine. Despite this progress, intuitive …
FAIRification of health-related data using semantic web technologies in the Swiss Personalized Health Network
Abstract The Swiss Personalized Health Network (SPHN) is a government-funded initiative
develo** federated infrastructures for a responsible and efficient secondary use of health …
develo** federated infrastructures for a responsible and efficient secondary use of health …
Review of statistical learning methods in integrated omics studies (an integrated information science)
ISL Zeng, T Lumley - Bioinformatics and biology insights, 2018 - journals.sagepub.com
Integrated omics is becoming a new channel for investigating the complex molecular system
in modern biological science and sets a foundation for systematic learning for precision …
in modern biological science and sets a foundation for systematic learning for precision …
Community-driven roadmap for integrated disease maps
Abstract The Disease Maps Project builds on a network of scientific and clinical groups that
exchange best practices, share information and develop systems biomedicine tools. The …
exchange best practices, share information and develop systems biomedicine tools. The …
-Omics biomarker identification pipeline for translational medicine
Background Translational medicine (TM) is an emerging domain that aims to facilitate
medical or biological advances efficiently from the scientist to the clinician. Central to the TM …
medical or biological advances efficiently from the scientist to the clinician. Central to the TM …
Analysis and visualization implementation of medical big data resource sharing mechanism based on deep learning
Y Yang, T Chen - IEEE Access, 2019 - ieeexplore.ieee.org
With the development of information technology, the informationization of the medical
industry is also constantly develo** rapidly, and medical data is growing exponentially. In …
industry is also constantly develo** rapidly, and medical data is growing exponentially. In …
What did we learn from multiple omics studies in asthma?
More than a decade has passed since the finalization of the Human Genome Project. Omics
technologies made a huge leap from trendy and very expensive to routinely executed and …
technologies made a huge leap from trendy and very expensive to routinely executed and …