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Fibroblast growth factor in diabetic foot ulcer: progress and therapeutic prospects
Y Liu, Y Liu, J Deng, W Li, X Nie - Frontiers in endocrinology, 2021 - frontiersin.org
Diabetic foot ulcer (DFU) is a combination of neuropathy and various degrees of peripheral
vasculopathy in diabetic patients resulting in lower extremity infection, ulcer formation, and …
vasculopathy in diabetic patients resulting in lower extremity infection, ulcer formation, and …
[HTML][HTML] Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases
AL Cardoso, A Fernandes, JA Aguilar-Pimentel… - Ageing research …, 2018 - Elsevier
Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …
valuable method for identifying elderly people at risk for increased vulnerability, disease …
[HTML][HTML] Retinopathy of prematurity: A review of pathophysiology and signaling pathways
Retinopathy of prematurity (ROP) is a vasoproliferative disorder of the retina and a leading
cause of visual impairment and childhood blindness worldwide. The disease is …
cause of visual impairment and childhood blindness worldwide. The disease is …
Targeting FGF21 in cardiovascular and metabolic diseases: from mechanism to medicine
H Tan, T Yue, Z Chen, W Wu, S Xu… - International Journal of …, 2023 - pmc.ncbi.nlm.nih.gov
Cardiovascular and metabolic disease (CVMD) is becoming increasingly prevalent in
developed and develo** countries with high morbidity and mortality. In recent years …
developed and develo** countries with high morbidity and mortality. In recent years …
Photoreceptor cells and RPE contribute to the development of diabetic retinopathy
D Tonade, TS Kern - Progress in retinal and eye research, 2021 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness. It has long been regarded as
vascular disease, but work in the past years has shown abnormalities also in the neural …
vascular disease, but work in the past years has shown abnormalities also in the neural …
Diabetic retinopathy: Involved cells, biomarkers, and treatments
J Ren, S Zhang, Y Pan, M **, J Li, Y Luo… - Frontiers in …, 2022 - frontiersin.org
Diabetic retinopathy (DR), a leading cause of vision loss and blindness worldwide, is
caused by retinal neurovascular unit dysfunction, and its cellular pathology involves at least …
caused by retinal neurovascular unit dysfunction, and its cellular pathology involves at least …
Contribution of Müller cells in the diabetic retinopathy development: focus on oxidative stress and inflammation
Diabetic retinopathy is a neurovascular complication of diabetes and the main cause of
vision loss in adults. Glial cells have a key role in maintenance of central nervous system …
vision loss in adults. Glial cells have a key role in maintenance of central nervous system …
New developments in the biology of fibroblast growth factors
DM Ornitz, N Itoh - WIREs mechanisms of disease, 2022 - Wiley Online Library
The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
Dyslipidemia in retinal metabolic disorders
The light‐sensitive photoreceptors in the retina are extremely metabolically demanding and
have the highest density of mitochondria of any cell in the body. Both physiological and …
have the highest density of mitochondria of any cell in the body. Both physiological and …
Retinopathy of prematurity: Metabolic risk factors
At preterm birth, the retina is incompletely vascularized. Retinopathy of prematurity (ROP) is
initiated by the postnatal suppression of physiological retinal vascular development that …
initiated by the postnatal suppression of physiological retinal vascular development that …