Designing the next-generation clinical care pathway for Alzheimer's disease

H Hampel, R Au, S Mattke, WM van der Flier, P Aisen… - Nature Aging, 2022 - nature.com
The reconceptualization of Alzheimer's disease (AD) as a clinical and biological construct
has facilitated the development of biomarker-guided, pathway-based targeted therapies …

Hypertension-induced cognitive impairment: from pathophysiology to public health

Z Ungvari, P Toth, S Tarantini, CI Prodan… - Nature Reviews …, 2021 - nature.com
Hypertension affects two-thirds of people aged> 60 years and significantly increases the risk
of both vascular cognitive impairment and Alzheimer's disease. Hypertension compromises …

Association of race and ethnicity with incidence of dementia among older adults

E Kornblith, A Bahorik, WJ Boscardin, F **a, DE Barnes… - Jama, 2022 - jamanetwork.com
Importance The racial and ethnic diversity of the US, including among patients receiving
their care at the Veterans Health Administration (VHA), is increasing. Dementia is a …

2018 Alzheimer's disease facts and figures

Alzheimer's Association - Alzheimer's & Dementia, 2018 - Elsevier
This article describes the public health impact of Alzheimer's disease (AD), including
incidence and prevalence, mortality and morbidity, costs of care, and the overall impact on …

Risk factors associated with Alzheimer disease and related dementias by sex and race and ethnicity in the US

RA Nianogo, A Rosenwohl-Mack, K Yaffe… - JAMA …, 2022 - jamanetwork.com
Importance Previous estimates suggested that 1 in 3 cases of Alzheimer disease and related
dementia (ADRDs) in the US are associated with modifiable risk factors, the most prominent …

Effect of aspirin on disability-free survival in the healthy elderly

JJ McNeil, RL Woods, MR Nelson… - … England Journal of …, 2018 - Mass Medical Soc
Background Information on the use of aspirin to increase healthy independent life span in
older persons is limited. Whether 5 years of daily low-dose aspirin therapy would extend …

Racial and ethnic differences in amyloid PET positivity in individuals with mild cognitive impairment or dementia: a secondary analysis of the Imaging Dementia …

CH Wilkins, CC Windon, P Dilworth-Anderson… - JAMA …, 2022 - jamanetwork.com
Importance Racial and ethnic groups with higher rates of clinical Alzheimer disease (AD) are
underrepresented in studies of AD biomarkers, including amyloid positron emission …

2016 Alzheimer's disease facts and figures

Alzheimer's Association - Alzheimer's & Dementia, 2016 - Elsevier
This report describes the public health impact of Alzheimer's disease, including incidence
and prevalence, mortality rates, costs of care, and the overall impact on caregivers and …

Black and White individuals differ in dementia prevalence, risk factors, and symptomatic presentation

JC Lennon, SL Aita, VAD Bene, T Rhoads… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction Although dementia prevalence differs by race, it remains unclear whether
cognition and neuropsychiatric symptom severity differ between Black and White individuals …

[HTML][HTML] Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: update and areas of immediate need

GM Babulal, YT Quiroz, BC Albensi… - Alzheimer's & …, 2019 - Elsevier
Alzheimer's disease and related dementias (ADRDs) are a global crisis facing the aging
population and society as a whole. With the numbers of people with ADRDs predicted to rise …