Pharmacological treatment of tremor in Parkinson's disease revisited

W Pirker, R Katzenschlager… - Journal of Parkinson's …, 2023 - journals.sagepub.com
The pathophysiology of Parkinson's disease (PD) tremor remains incompletely understood
and there is a lack of clinical trials specifically addressing its pharmacological treatment …

Cellular and molecular basis of neurodegeneration in Parkinson disease

XS Zeng, WS Geng, JJ Jia, L Chen… - Frontiers in aging …, 2018 - frontiersin.org
It has been 200 years since Parkinson disease (PD) was described by Dr. Parkinson in
1817. The disease is the second most common neurodegenerative disease characterized …

[HTML][HTML] The pathophysiology of Parkinson's disease tremor

MF Dirkx, M Bologna - Journal of the Neurological Sciences, 2022 - Elsevier
Tremor is one of the primary motor symptoms of Parkinson's disease (PD), and it is
characterized by a highly phenomenological heterogeneity. Clinical and experimental …

A review on pathology, mechanism, and therapy for cerebellum and tremor in Parkinson's disease

Y Zhong, H Liu, G Liu, L Zhao, C Dai, Y Liang… - npj Parkinson's …, 2022 - nature.com
Tremor is one of the core symptoms of Parkinson's disease (PD), but its mechanism is poorly
understood. The cerebellum is a growing focus in PD-related researches and is reported to …

Tremor in Parkinson's disease: from pathophysiology to advanced therapies

AH Abusrair, W Elsekaily… - Tremor and Other …, 2022 - pmc.ncbi.nlm.nih.gov
Background: Tremor is one of the most prevalent symptoms in Parkinson's Disease (PD).
The progression and management of tremor in PD can be challenging, as response to …

Network imaging biomarkers: insights and clinical applications in Parkinson's disease

KA Schindlbeck, D Eidelberg - The Lancet Neurology, 2018 - thelancet.com
Parkinson's disease presents several practical challenges: it can be difficult to distinguish
from atypical parkinsonian syndromes, clinical ratings can be insensitive as markers of …

Bimetallic CoMoO4 Nanozymes Enhanced Luminol Chemiluminescence for the Detection of Dopamine

Z Dong, S **a, AMA Alboull, IM Mostafa… - ACS Applied Nano …, 2024 - ACS Publications
Transition-metal-based nanozymes show great potential for chemiluminescence (CL)
detection due to their stability, excellent catalytic properties, good biocompatibility, and facile …

Human brain connectivity: Clinical applications for clinical neurophysiology

M Hallett, W de Haan, G Deco, R Dengler… - Clinical …, 2020 - Elsevier
This manuscript is the second part of a two-part description of the current status of
understanding of the network function of the brain in health and disease. We start with the …

Physiological mechanisms of thalamic ventral intermediate nucleus stimulation for tremor suppression

L Milosevic, SK Kalia, M Hodaie, AM Lozano… - Brain, 2018 - academic.oup.com
Ventral intermediate thalamic deep brain stimulation is a standard therapy for the treatment
of medically refractory essential tremor and tremor-dominant Parkinson's disease. Despite …

Changing views of the pathophysiology of Parkinsonism

T Wichmann - Movement Disorders, 2019 - Wiley Online Library
Studies of the pathophysiology of parkinsonism (specifically akinesia and bradykinesia)
have a long history and primarily model the consequences of dopamine loss in the basal …