Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies
Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …
personalized medicine. This review covers the principles, advantages, and drawbacks of …
Drug delivery and targeting.
R Langer - Nature, 1998 - europepmc.org
When a pharmaceutical agent is encapsulated within, or attached to, a polymer or lipid, drug
safety and efficacy can be greatly improved and new therapies are possible. This has …
safety and efficacy can be greatly improved and new therapies are possible. This has …
Polymeric conjugates for drug delivery
The field of polymer therapeutics has evolved over the past decade and has resulted in the
development of polymer–drug conjugates with a wide variety of architectures and chemical …
development of polymer–drug conjugates with a wide variety of architectures and chemical …
Biomimetic materials for tissue engineering
The development of biomaterials for tissue engineering applications has recently focused on
the design of biomimetic materials that are capable of eliciting specific cellular responses …
the design of biomimetic materials that are capable of eliciting specific cellular responses …
Nanoparticle-assisted combination therapies for effective cancer treatment
Combination chemotherapy and nanoparticle drug delivery are two areas that have shown
significant promise in cancer treatment. Combined therapy of two or more drugs promotes …
significant promise in cancer treatment. Combined therapy of two or more drugs promotes …
Advances in biomaterials, drug delivery, and bionanotechnology
Biomaterials are widely used in numerous medical applications. Chemical engineering has
played a central role in this research and development. Polymers as biomaterials, materials …
played a central role in this research and development. Polymers as biomaterials, materials …
Stimuli-responsive prodrug-based cancer nanomedicine
The rapid development of nanotechnology results in the emergence of nanomedicines, but
the effective delivery of drugs to tumor sites remains a great challenge. Prodrug-based …
the effective delivery of drugs to tumor sites remains a great challenge. Prodrug-based …
HPMA copolymers: origins, early developments, present, and future
J Kopeček, P Kopečková - Advanced drug delivery reviews, 2010 - Elsevier
The overview covers the discovery of N-(2-hydroxypropyl) methacrylamide (HPMA)
copolymers, initial studies on their synthesis, evaluation of biological properties, and …
copolymers, initial studies on their synthesis, evaluation of biological properties, and …
Effective drug delivery by PEGylated drug conjugates
RB Greenwald, YH Choe, J McGuire… - Advanced drug delivery …, 2003 - Elsevier
The current review presents an update of drug delivery using poly (ethylene glycol)(PEG),
that focuses on recent developments in both protein and organic drugs. Certainly the past 10 …
that focuses on recent developments in both protein and organic drugs. Certainly the past 10 …
Intelligent polymeric micelles from functional poly (ethylene glycol)-poly (amino acid) block copolymers
This review describes our recent efforts on the design and preparation of intelligent
polymeric micelles from functional poly (ethylene glycol)-poly (amino acid)(PEG-PAA) block …
polymeric micelles from functional poly (ethylene glycol)-poly (amino acid)(PEG-PAA) block …