Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused
by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and …

Abstract Purpose of Review Obesity is accompanied by atherogenic dyslipidemia, a specific
lipid disorder characterized by both quantitative and qualitative changes of plasma …

Aims Cholesterol carried in triglyceride-rich lipoproteins, also called remnant cholesterol, is
being increasingly acknowledged as an important causal risk factor for atherosclerosis …

Elevations in plasma triglyceride are the result of overproduction and impaired clearance of
triglyceride-rich lipoproteins—very low-density lipoproteins (VLDL) and chylomicrons …

Abstract Background and aims This European Atherosclerosis Society (EAS) Task Force
provides practical guidance for combination therapy for elevated low-density lipoprotein …

Aims We tested the hypothesis that high directly measured remnant cholesterol is
associated with increased risk of ischaemic heart disease (IHD) and myocardial infarction …

Background Intestinal microbiota have been found to be linked to cardiovascular disease via
conversion of the dietary compounds choline and carnitine to the atherogenic metabolite …

Background Triglycerides, cholesterol, and their metabolism are linked due to shared
packaging and transport within circulating lipoprotein particles. While a case for a causal …

In the era of precision medicine, treatments that target specific modifiable characteristics of
high-risk patients have the potential to lower further the residual risk of atherosclerotic …

Objective High remnant cholesterol concentrations are associated with high risk of ischemic
heart disease, but whether this is also the case for ischemic stroke is unknown. We tested …