On vasa vasorum: A history of advances in understanding the vessels of vessels

JA Phillippi - Science Advances, 2022 - science.org
The vasa vasorum are a vital microvascular network supporting the outer wall of larger blood
vessels. Although these dynamic microvessels have been studied for centuries, the …

Molecular imaging of aortic aneurysm and its translational power for clinical risk assessment

V Rastogi, SJM Stefens, J Houwaart… - Frontiers in …, 2022 - frontiersin.org
Aortic aneurysms (AAs) are dilations of the aorta, that are often fatal upon rupture.
Diagnostic radiological techniques such as ultrasound (US), magnetic resonance imaging …

[64Cu]Cu-ATSM: an emerging theranostic agent for cancer and neuroinflammation

F **e, W Wei - European Journal of Nuclear Medicine and Molecular …, 2022 - Springer
Neuroinflammation is a key biological process in response to cell infection or injury that
involves all the cells present within the central nervous system (CNS), including microglia …

Uncovering atherosclerotic cardiovascular disease by PET imaging

A Maier, AJP Teunissen, SA Nauta, E Lutgens… - Nature Reviews …, 2024 - nature.com
Assessing atherosclerosis severity is essential for precise patient stratification. Specifically,
there is a need to identify patients with residual inflammation because these patients remain …

Targeting ferroptosis in cardio‐metabolic‐diseases: Mechanisms and therapeutic prospects

JB Zhang, J Tong, DY Sun, JT Fu… - Medicinal research …, 2023 - Wiley Online Library
Abstract Cardio‐metabolic‐diseases (cardio‐metabolic‐diseases) are leading causes of
death and disability worldwide and impose a tremendous burden on whole society as well …

Molecular and nonmolecular imaging of macrophages in atherosclerosis

Z Li, H Tang, Y Tu - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Atherosclerosis is a major cause of ischemic heart disease, and the increasing medical
burden associated with atherosclerotic cardiovascular disease has become a major public …

Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis

QX Ji, FY Zeng, J Zhou, WB Wu, XJ Wang… - Cell Death & …, 2023 - nature.com
Smooth muscle cell (SMC) phenotypic switch from a quiescent 'contractile'phenotype to a
dedifferentiated and proliferative state underlies the development of cardiovascular …

Insight into tumor hypoxia: Radionuclide-based biomarker as diagnostic tools

P Saxena, S Gambhir, M Dixit - Current Topics in Medicinal …, 2023 - ingentaconnect.com
The radiolabeled tracers have been extensively utilized to access various physiological and
pathological conditions non-invasively, such as cancers, inflammation, and organ-specific …

[HTML][HTML] Non-FDG hypoxia tracers

KMG Mokoala, MM Sathekge - Seminars in Nuclear Medicine, 2024 - Elsevier
Hypoxia plays a critical role in tumor biology, influencing cancer progression, treatment
resistance, and patient prognosis. While 18-Fluorine fluoredeoxyglucose ([18F] F-FDG) PET …

Emerging nuclear medicine imaging of atherosclerotic plaque formation

A Kondakov, A Berdalin, M Beregov, V Lelyuk - Journal of Imaging, 2022 - mdpi.com
Atherosclerosis is a chronic widespread cardiovascular disease and a major predisposing
factor for cardiovascular events, among which there are myocardial infarction and ischemic …