Extracellular vesicles as tools and targets in therapy for diseases
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
New insights into mechanisms of cisplatin resistance: from tumor cell to microenvironment
SH Chen, JY Chang - International journal of molecular sciences, 2019 - mdpi.com
Although cisplatin has been a pivotal chemotherapy drug in treating patients with various
types of cancer for decades, drug resistance has been a major clinical impediment. In …
types of cancer for decades, drug resistance has been a major clinical impediment. In …
Extracellular vesicles in ovarian cancer chemoresistance, metastasis, and immune evasion
W Tian, N Lei, J Zhou, M Chen, R Guo, B Qin, Y Li… - Cell Death & …, 2022 - nature.com
Chemoresistance and metastasis are the major challenges for the current ovarian cancer
treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is …
treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is …
Extracellular vesicles and particles impact the systemic landscape of cancer
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
Insight into extracellular vesicle-cell communication: from cell recognition to intracellular fate
Extracellular vesicles (EVs) are heterogamous lipid bilayer-enclosed membranous
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …
[HTML][HTML] Cellular landsca** of cisplatin resistance in cervical cancer
Cervical cancer (CC) caused by human papillomavirus (HPV) is one of the largest causes of
malignancies in women worldwide. Cisplatin is one of the widely used drugs for the …
malignancies in women worldwide. Cisplatin is one of the widely used drugs for the …
Hypoxia alters the release and size distribution of extracellular vesicles in pancreatic cancer cells to support their adaptive survival
Pancreatic tumors are highly desmoplastic and poorly‐vascularized, and therefore must
develop adaptive mechanisms to sustain their survival under hypoxic condition. Extracellular …
develop adaptive mechanisms to sustain their survival under hypoxic condition. Extracellular …
Dying tumor cell-derived exosomal miR-194-5p potentiates survival and repopulation of tumor repopulating cells upon radiotherapy in pancreatic cancer
M Jiang, Y Chen, J Dai, D Gu, Z Mei, F Liu, Q Huang… - Molecular cancer, 2020 - Springer
Background Tumor repopulation is a major cause of radiotherapy failure. Previous
investigations highlighted that dying tumor cells played vital roles in tumor repopulation …
investigations highlighted that dying tumor cells played vital roles in tumor repopulation …
Differential intracellular trafficking of extracellular vesicles in microglia and astrocytes
Extracellular vesicles (EVs) have emerged as key players in cell-to-cell communication in
both physiological and pathological processes in the Central Nervous System. Thus far, the …
both physiological and pathological processes in the Central Nervous System. Thus far, the …
Ionizing radiation increases the activity of exosomal secretory pathway in MCF-7 human breast cancer cells: a possible way to communicate resistance against …
Radiation therapy, which applies high-energy rays, to eradicate tumor cells, is considered
an essential therapy for the patients with breast cancer. Most tumor cells secrete exosomes …
an essential therapy for the patients with breast cancer. Most tumor cells secrete exosomes …