[HTML][HTML] Biofabrication methods for reconstructing extracellular matrix mimetics

A Aazmi, D Zhang, C Mazzaglia, M Yu, Z Wang… - Bioactive Materials, 2024 - Elsevier
In the human body, almost all cells interact with extracellular matrices (ECMs), which have
tissue and organ-specific compositions and architectures. These ECMs not only function as …

Recent advances in bioprinting techniques: approaches, applications and future prospects

J Li, M Chen, X Fan, H Zhou - Journal of translational medicine, 2016 - Springer
Bioprinting technology shows potential in tissue engineering for the fabrication of scaffolds,
cells, tissues and organs reproducibly and with high accuracy. Bioprinting technologies are …

Organ/body-on-a-chip based on microfluidic technology for drug discovery

H Kimura, Y Sakai, T Fujii - Drug metabolism and pharmacokinetics, 2018 - Elsevier
Although animal experiments are indispensable for preclinical screening in the drug
discovery process, various issues such as ethical considerations and species differences …

Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform

K Achberger, C Probst, J Haderspeck, S Bolz, J Rogal… - elife, 2019 - elifesciences.org
The devastating effects and incurable nature of hereditary and sporadic retinal diseases
such as Stargardt disease, age-related macular degeneration or retinitis pigmentosa …

Microfluidic organ-on-a-chip models of human liver tissue

E Moradi, S Jalili-Firoozinezhad, M Solati-Hash** - Acta biomaterialia, 2020 - Elsevier
The liver is the largest internal organ of the body with complex microarchitecture and
function that plays critical roles in drug metabolism. Hepatotoxicity and drug-induced liver …

Microfabrication of human organs-on-chips

D Huh, HJ Kim, JP Fraser, DE Shea, M Khan… - Nature protocols, 2013 - nature.com
Abstract'Organs-on-chips' are microengineered biomimetic systems containing microfluidic
channels lined by living human cells, which replicate key functional units of living organs to …

[HTML][HTML] From 3D cell culture to organs-on-chips

D Huh, GA Hamilton, DE Ingber - Trends in cell biology, 2011 - cell.com
3D cell-culture models have recently garnered great attention because they often promote
levels of cell differentiation and tissue organization not possible in conventional 2D culture …

[HTML][HTML] 3D bioprinting in tissue engineering for medical applications: the classic and the hybrid

Z **e, M Gao, AO Lobo, TJ Webster - Polymers, 2020 - mdpi.com
Three-dimensional (3D) printing, as one of the most popular recent additive manufacturing
processes, has shown strong potential for the fabrication of biostructures in the field of tissue …

[HTML][HTML] Microfluidic organ-on-a-chip system for disease modeling and drug development

Z Li, J Hui, P Yang, H Mao - Biosensors, 2022 - mdpi.com
An organ-on-a-chip is a device that combines micro-manufacturing and tissue engineering
to replicate the critical physiological environment and functions of the human organs …

Towards artificial tissue models: past, present, and future of 3D bioprinting

A Arslan-Yildiz, R El Assal, P Chen, S Guven… - …, 2016 - iopscience.iop.org
Regenerative medicine and tissue engineering have seen unprecedented growth in the past
decade, driving the field of artificial tissue models towards a revolution in future medicine …