The ichthyoses are a large, heterogeneous group of skin cornification disorders. They can
be inherited or acquired, and result in defective keratinocyte differentiation and abnormal …

Ichthyosis covers a wide spectrum of diseases affecting the cornification of the skin. In recent
years, new advances in understanding the pathophysiology of ichthyosis have been made …

Recent progress in the genetics of autosomal recessive congenital ichthyosis (ARCI) has
illustrated the power of genetic strategies for the investigation of newly recognized metabolic …

These guidelines for the management of congenital ichthyoses have been developed by a
multidisciplinary group of European experts following a systematic review of the current …

Topical and systemic retinoids have long been used in the treatment of ichthyoses and other
disorders of cornification. Due to the need for long‐term use of retinoids for these disorders …

Netherton syndrome (NS) is a genetic, multisystemic disease classically distinguished by a
triad of clinical manifestations: congenital ichthyosiform erythroderma, hair shaft …

3 Begg C, Hummer A, Mujumdar U et al. A design for cancer case–control studies using only
incident case: experience with the GEM study of melanoma. Int J Epidemiol 2006; 35: 756 …

Netherton syndrome (NS) is a rare genodermatosis with an autosomal recessive pattern of
inheritance caused by pathogenic variants in the SPINK5 gene. It is characterized by a triad …

Genodermatoses are rare inherited skin diseases that frequently affect other organs. They
often have marked effects on wellbeing and may cause early death. Progress in molecular …

The understanding of monogenetic disorders of cornification, including the group of
diseases called ichthyoses, has expanded greatly in recent years. Studies of the aetiology of …