NHC-catalyzed generation of α, β-unsaturated acylazoliums for the enantioselective synthesis of heterocycles and carbocycles
Conspectus This Account is aimed at highlighting the recent developments in the N-
heterocyclic carbene (NHC)-catalyzed generation of α, β-unsaturated acylazolium …
heterocyclic carbene (NHC)-catalyzed generation of α, β-unsaturated acylazolium …
N-heterocyclic carbene-catalyzed arene formation reactions
T Li, Z **, YR Chi - Science China Chemistry, 2022 - Springer
N-heterocyclic carbene-catalyzed reactions for the formation of aromatic compounds are
reviewed. The reactions are subdivided into 4 types based on their activation modes. A brief …
reviewed. The reactions are subdivided into 4 types based on their activation modes. A brief …
Enantioselective access to triaryl-2-pyrones with monoaxial or contiguous C–C diaxes via oxidative NHC catalysis
SC Zhang, S Liu, X Wang, SJ Wang, H Yang, L Li… - ACS …, 2023 - ACS Publications
We present herein an unprecedented stereoselective synthesis of triaryl-2-pyrones with
monoaxial or contiguous diaxes from readily available starting materials. This N-heterocyclic …
monoaxial or contiguous diaxes from readily available starting materials. This N-heterocyclic …
Highly enantioselective [5+ 2] annulations through cooperative N-heterocyclic carbene (NHC) organocatalysis and palladium catalysis
The highly enantioselective [5+ 2] annulation of enals with vinylethylene carbonates through
a cooperative N-heterocyclic carbene (NHC)/Pd catalytic system is reported. The use of a …
a cooperative N-heterocyclic carbene (NHC)/Pd catalytic system is reported. The use of a …
NHC‐catalyzed desymmetrization of n‐aryl maleimides leading to the atroposelective synthesis of N‐Aryl succinimides
Although the construction of axially chiral C− C bonds leading to the atroposelective
synthesis of biaryls and allied compounds are well‐known, the related synthesis of …
synthesis of biaryls and allied compounds are well‐known, the related synthesis of …
Stereodivergent synthesis of 1, 4-dicarbonyls by traceless charge–accelerated sulfonium rearrangement
D Kaldre, I Klose, N Maulide - Science, 2018 - science.org
The chemistry of the carbonyl group is essential to modern organic synthesis. The
preparation of substituted, enantioenriched 1, 3-or 1, 5-dicarbonyls is well developed, as …
preparation of substituted, enantioenriched 1, 3-or 1, 5-dicarbonyls is well developed, as …
Diastereo-and atroposelective synthesis of bridged biaryls bearing an eight-membered lactone through an organocatalytic cascade
We present herein an unprecedented stereoselective synthesis of bridged biaryls with
defined axial and central chirality from readily available starting materials. This N …
defined axial and central chirality from readily available starting materials. This N …
N-Heterocyclic carbene (NHC) organocatalysis using aliphatic aldehydes
Catalysis using N-heterocyclic carbenes (NHCs) has been widely employed for the
umpolung of aldehydes, and these reactions proceed via the generation of nucleophilic …
umpolung of aldehydes, and these reactions proceed via the generation of nucleophilic …
Asymmetric Synthesis of Spirobenzazepinones with Atroposelectivity and Spiro‐1, 2‐Diazepinones by NHC‐Catalyzed [3+ 4] Annulation Reactions
L Wang, S Li, M Blümel, AR Philipps… - Angewandte …, 2016 - Wiley Online Library
A strategy for the NHC‐catalyzed asymmetric synthesis of spirobenzazepinones, spiro‐1, 2‐
diazepinones, and spiro‐1, 2‐oxazepinones has been developed via [3+ 4]‐cycloaddition …
diazepinones, and spiro‐1, 2‐oxazepinones has been developed via [3+ 4]‐cycloaddition …
Enantioselective Synthesis of Spirocyclohexadienones by NHC‐Catalyzed Formal [3+ 3] Annulation Reaction of Enals
The enantioselective synthesis of pyrazolone‐fused spirocyclohexadienones was
demonstrated by the reaction of α, β‐unsaturated aldehydes with α‐arylidene pyrazolinones …
demonstrated by the reaction of α, β‐unsaturated aldehydes with α‐arylidene pyrazolinones …