Protozoan parasites that profoundly affect mankind represent an exceptionally diverse group
of organisms, including Plasmodium, Toxoplasma, Entamoeba, Giardia, trypanosomes, and …

African trypanosomes are major pathogens of humans and livestock and represent a model
for studies of unusual protozoal biology. We describe a high-throughput phenoty** …

Parasites are responsible for the most neglected tropical diseases, affecting over a billion
people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible …

Abstract The Molecular Parasitology conference was first held at the Marine Biological
laboratory, Woods Hole, USA 25 years ago. Since that first meeting, the conference has …

The concept of disease-specific chemotherapy was developed a century ago. Dyes and
arsenical compounds that displayed selectivity against trypanosomes were central to this …

The African trypanosome, Trypanosoma brucei, maintains an integral link between cell cycle
regulation and differentiation during its intricate life cycle. Whilst extensive changes in …

African trypanosomes cause lethal and neglected tropical diseases, known as slee**
sickness in humans and nagana in animals. Current therapies are limited, but fortunately …

Human African trypanosomiasis, endemic to sub-Saharan Africa, is invariably fatal if
untreated. Its causative agent is the protozoan parasite Trypanosoma brucei. Eflornithine is …

While gene expression is a fundamental and tightly controlled cellular process that is
regulated at multiple steps, the exact contribution of each step remains unknown in any …

African trypanosomes cause slee** sickness in humans, a disease that is typically fatal
without chemotherapy. Unfortunately, drug resistance is common and melarsoprol-resistant …