The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions

BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Hydrogels for tissue engineering

KY Lee, DJ Mooney - Chemical reviews, 2001 - ACS Publications
Every year, millions of patients suffer the loss or failure of an organ or tissue as a result of
accidents or disease. Over 8 million surgical procedures are performed to treat these …

Rethinking amide bond synthesis

VR Pattabiraman, JW Bode - Nature, 2011 - nature.com
One of the most important reactions in organic chemistry—amide bond formation—is often
overlooked as a contemporary challenge because of the widespread occurrence of amides …

From precision polymers to complex materials and systems

JF Lutz, JM Lehn, EW Meijer… - Nature Reviews Materials, 2016 - nature.com
Complex chemical systems, such as living biological matter, are highly organized structures
based on discrete molecules in constant dynamic interactions. These natural materials can …

Nitroxide-mediated polymerization

J Nicolas, Y Guillaneuf, C Lefay, D Bertin… - Progress in Polymer …, 2013 - Elsevier
Nitroxide-mediated polymerization (NMP) is a controlled/living radical polymerization
(CLRP) technique that enables the design of well-defined, functional and complex …

Star polymers

JM Ren, TG McKenzie, Q Fu, EHH Wong, J Xu… - Chemical …, 2016 - ACS Publications
Recent advances in controlled/living polymerization techniques and highly efficient coupling
chemistries have enabled the facile synthesis of complex polymer architectures with …

Stimuli-reponsive polymers and their bioconjugates

ES Gil, SM Hudson - Progress in polymer science, 2004 - Elsevier
Stimuli responsive polymers can provide a variety of applications for the biomedical fields.
The interest in these polymers has exponentially increased due to their promising potential …

Recent approaches in designing bioadhesive materials inspired by mussel adhesive protein

P Kord Forooshani, BP Lee - Journal of Polymer Science Part A …, 2017 - Wiley Online Library
Marine mussels secret protein‐based adhesives, which enable them to anchor to various
surfaces in a saline, intertidal zone. Mussel foot proteins (Mfps) contain a large abundance …

Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids

AR Mazo, S Allison-Logan, F Karimi… - Chemical society …, 2020 - pubs.rsc.org
Polypeptides have attracted considerable attention in recent decades due to their inherent
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …

[HTML][HTML] Poly (α-l-lysine)-based nanomaterials for versatile biomedical applications: Current advances and perspectives

M Zheng, M Pan, W Zhang, H Lin, S Wu, C Lu, S Tang… - Bioactive Materials, 2021 - Elsevier
Abstract Poly (α-l-lysine)(PLL) is a class of water-soluble, cationic biopolymer composed of α-
l-lysine structural units. The previous decade witnessed tremendous progress in the …