Deep learning-based denoising in projection-domain and reconstruction-domain for low-dose myocardial perfusion SPECT

J Sun, H Jiang, Y Du, CY Li, TH Wu, YH Liu… - Journal of Nuclear …, 2023 - Springer
Background Low-dose (LD) myocardial perfusion (MP) SPECT suffers from high noise level,
leading to compromised diagnostic accuracy. Here we investigated the denoising …

A review of state-of-the-art resolution improvement techniques in SPECT imaging

Z Cheng, P Chen, J Yan - EJNMMI physics, 2025 - Springer
Single photon emission computed tomography (SPECT), a technique capable of capturing
functional and molecular information, has been widely adopted in theranostics applications …

A look at radiation detectors and their applications in medical imaging

N Usanase, B Uzun, DU Ozsahin, I Ozsahin - Japanese Journal of …, 2024 - Springer
The effectiveness and precision of disease diagnosis and treatment have increased, thanks
to developments in clinical imaging over the past few decades. Science is develo** and …

Characterization of accurate 3D collimator-detector response function for single-and multi-lofthole collimated SPECT cameras

M Saed, H Mahani, A Sadremomtaz - Japanese Journal of Radiology, 2024 - Springer
Purpose Collimator-detector response function (CDRF) of a SPECT scanner refers to the
image generated from a point source of activity. This research aims to characterize the …

Fast myocardial perfusion SPECT denoising using an attention-guided generative adversarial network

J Sun, BH Yang, CY Li, Y Du, YH Liu, TH Wu… - Frontiers in …, 2023 - frontiersin.org
Purpose Deep learning-based denoising is promising for myocardial perfusion (MP) SPECT.
However, conventional convolutional neural network (CNN)-based methods use fixed-sized …

Performance evaluation of a novel multi-pinhole SPECT system

N Jiang, H Liu, M Xue, C Li, L Gao, F Liu, J Wu… - Nuclear Instruments and …, 2024 - Elsevier
In this work, the performance of a novel multi-pinhole SPECT (MPH SPECT) system based
on Insight NM/CT Pro (Bei**g Novel Medical Equipment Ltd) was evaluated. The sensitivity …

Multiple-pinhole collimators improve intra-and between-rater agreement and the certainty of the visual interpretation in dopamine transporter SPECT

F Mathies, I Apostolova, L Dierck, J Jacobi, K Kuen… - EJNMMI research, 2022 - Springer
Background Multiple-pinhole (MPH) collimators improve the resolution–sensitivity trade-off
compared to parallel-hole collimators. This study evaluated the impact of MPH collimators …

Side-Chain Modified [99mTc]Tc-DT1 Mimics: A Comparative Study in NTS1R-Positive Models

P Kanellopoulos, BA Nock, M Rouchota… - International Journal of …, 2023 - mdpi.com
Radiolabeled neurotensin analogs have been developed as candidates for theranostic use
against neurotensin subtype 1 receptor (NTS1R)-expressing cancer. However, their fast …

In Vivo Evaluation of Gallium‐68‐Labeled IRDye800CW as a Necrosis Avid Contrast Agent in Solid Tumors

MCM Stroet, E de Blois, J Haeck… - Contrast Media & …, 2021 - Wiley Online Library
Necrosis only occurs in pathological situations and is directly related to disease severity
and, therefore, is an important biomarker. Tumor necrosis occurs in most solid tumors due to …

Correction of multiplexing artefacts in multi-pinhole SPECT through temporal shuttering, de-multiplexing of projections, and alternating reconstruction

S Pells, N Zeraatkar, KS Kalluri… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. Single-photon emission computed tomography (SPECT) with pinhole collimators
can provide high-resolution imaging, but is often limited by low sensitivity. Acquiring …