Genome-wide association studies (GWAS) have been successful in deciphering the genetic
component of predisposition to many human complex diseases including prostate cancer …

Prostate cancer (PCa) is the most common non-cutaneous tumor among men worldwide
and, if diagnosed late, it exhibits a high mortality representing the sixth most lethal tumor in …

Cancer driver genes, ie, oncogenes and tumor suppressor genes, are involved in the
acquisition of important functions in tumors, providing a selective growth advantage …

Heterochromatin protein 1γ (HP1γ) has been implicated in carcinogenesis of various cancer
types. However, the role of HP1γ in prostate cancer (PCa) progression and the underlying …

Background Multiple sclerosis (MS) is a chronic immune-mediated disease of the central
nervous system to which a genetic predisposition contributes. Over 200 genetic regions …

A remarkable proportion of factors causing genetic predisposition to breast cancer (BC) are
unknown in non-BRCA1/2 families. Exome sequencing was performed for 13 high-risk …

Background and aim Colorectal cancer (CRC) is a worldwide leading cause of mortality.
Genetic studies have associated single nucleotide polymorphisms in genes encoding …

Prostate cancer (PrCa) is one of the most common cancers in men, but little is known about
factors affecting its clinical outcomes. Genome-wide association studies have identified …

Background There is contradictory evidence of the effects that environmental factors—
dietary habits (ingestion rates of red meat, soy products, fish, etc.) and work environment …

Previous genome-wide association studies (GWAS) in populations of European descent
identified a lung cancer susceptibility locus at 15q25 that was biologically associated with …