The uptake of calcium into and extrusion of calcium from the mitochondrial matrix is a
fundamental biological process that has critical effects on cellular metabolism, signaling …

Calcium handling by mitochondria is a key feature in cell life. It is involved in energy
production for cell activity, in buffering and sha** cytosolic calcium rises and also in …

Mitochondria are double-membrane enclosed eukaryotic organelles with a central role in
numerous cellular functions. The ultrastructure of mitochondria varies considerably between …

The ability of mitochondria to capture Ca2+ ions has important functional implications for
cells, because mitochondria shape cellular Ca2+ signals by acting as a Ca2+ buffer and …

In creating mitochondria some 2 billion years ago, the first eukaryotes needed to establish
protein import machinery in the membranes of what was a bacterial endosymbiont. Some of …

Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

Proteomic analyses of different subcellular compartments, so-called organellar proteomics,
facilitate the understanding of cellular functions on a molecular level. In this work, various …

The mitochondrion is arguably the most complex organelle in the budding yeast cell
cytoplasm. It is essential for viability as well as respiratory growth. Its innermost aqueous …

Protein synthesis in mammalian mitochondria produces 13 proteins that are essential
subunits of the oxidative phosphorylation complexes. This review provides a detailed outline …

The terminal enzyme of the mitochondrial respiratory chain, cytochrome oxidase, transfers
electrons to molecular oxygen, generating water. Within the inner mitochondrial membrane …