After decades of intense effort, therapeutics that leverage the immune system to fight cancer
have now been conclusively demonstrated to be effective. Immuno-oncology has arrived …

Strides in melanoma surveillance, detection, and treatment continue to be made. The
American Joint Committee on Cancer Eighth Edition Cancer Staging System has improved …

Taking into consideration that the immune system plays a very important role in the
development of melanoma and non‐melanoma skin cancers, which have a high prevalence …

Despite its useful properties, imiquimod (IMQ), known as an anti-cancer drug, can be
harmful to the skin at high concentrations. Therefore, we have developed a novel …

In‐transit metastases (ITM) of cutaneous melanoma are locoregional recurrences confined
to the superficial lymphatics that occur in 3.4–6.2% of patients diagnosed with melanoma …

The recent coronavirus disease 2019 (COVID-19) pandemic has created a quandary for the
physician in terms of evaluating and treating cutaneous skin cancers, particularly …

The most frequent site of first melanoma recurrence is locoregional, and this is frequently a
harbinger of systemic recurrence. Local recurrence, satellitosis, and in-transit metastasis are …

Surgical excision represents the primary treatment for malignant melanoma. On occasion,
however, surgery may not be possible, and a different approach is required. Imiquimod is a …

This report surveys the role of topical and intralesional agents in the management of in-
transit melanoma. The extent and progression of in-transit disease is highly variable and …

IARS2, which encodes the mitochondrial form of isoleucyl-tRNA synthetase, has been found
to play an important role in a range of diseases, including cancer. However, the relationship …