Iron Oxide Nanoparticles as T1 Contrast Agents for Magnetic Resonance Imaging: Fundamentals, Challenges, Applications, and Prospectives
Gadolinium‐based chelates are a mainstay of contrast agents for magnetic resonance
imaging (MRI) in the clinic. However, their toxicity elicits severe side effects and the Food …
imaging (MRI) in the clinic. However, their toxicity elicits severe side effects and the Food …
[HTML][HTML] Magnetic iron oxide nanoparticles for imaging, targeting and treatment of primary and metastatic tumors of the brain
Magnetic nanoparticles in general, and iron oxide nanoparticles in particular, have been
studied extensively during the past 20 years for numerous biomedical applications. The …
studied extensively during the past 20 years for numerous biomedical applications. The …
A hepatocyte-targeting nanoparticle for enhanced hepatobiliary magnetic resonance imaging
H Zhang, Y Guo, J Jiao, Y Qiu, Y Miao, Y He… - Nature biomedical …, 2023 - nature.com
Hepatobiliary magnetic resonance imaging (MRI) can inform the diagnosis of liver tumours
in patients with liver cirrhosis and hepatitis. However, its clinical utility has been hampered …
in patients with liver cirrhosis and hepatitis. However, its clinical utility has been hampered …
Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to Macaca nemestrina
Extracellular vesicles (EVs) have potential in disease treatment since they can be loaded
with therapeutic molecules and engineered for retention by specific tissues. However …
with therapeutic molecules and engineered for retention by specific tissues. However …
Theranostic nanoparticles for RNA-based cancer treatment
Conspectus Certain genetic mutations lead to the development of cancer through
unchecked cell growth and division. Cancer is typically treated through surgical resection …
unchecked cell growth and division. Cancer is typically treated through surgical resection …
Charcot–Marie–Tooth neuropathies: current gene therapy advances and the route toward translation
Abstract Charcot–Marie–Tooth (CMT) neuropathies are a group of genetically and
phenotypically heterogeneous disorders that predominantly affect the peripheral nervous …
phenotypically heterogeneous disorders that predominantly affect the peripheral nervous …
Stimuli-controllable iron oxide nanoparticle assemblies: Design, manipulation and bio-applications
Despite its wide establishment over the years, iron oxide nanoparticle (IONP) still draws
extensive interest in the biomedical fields due to its biocompatibility, biodegradability …
extensive interest in the biomedical fields due to its biocompatibility, biodegradability …
Package delivered: folate receptor-mediated transporters in cancer therapy and diagnosis
Neoplasias pose a significant threat to aging society, underscoring the urgent need to
overcome the limitations of traditional chemotherapy through pioneering strategies …
overcome the limitations of traditional chemotherapy through pioneering strategies …
Polymersomes scalably fabricated via flash nanoprecipitation are non-toxic in non-human primates and associate with leukocytes in the spleen and kidney following …
Vesicular nanocarrier formulations confer the ability to deliver hydrophobic and hydrophilic
cargos simultaneously to cells of interest in vivo. While liposomal formulations reached the …
cargos simultaneously to cells of interest in vivo. While liposomal formulations reached the …
Therapeutic nanotechnologies for Alzheimer's disease: A critical analysis of recent trends and findings
Alzheimer's Disease (AD) is an irreversible neurodegenerative disease for which no
modifying therapies are presently available. Besides the identification of pathological …
modifying therapies are presently available. Besides the identification of pathological …