The role of genetics, epigenetics, and the environment in ASD: A mini review

AA Khogeer, IS AboMansour, DA Mohammed - Epigenomes, 2022 - mdpi.com
According to recent findings, variances in autism spectrum disorder (ASD) risk factors might
be determined by several factors, including molecular genetic variants. Accumulated …

Gut microbiota metabolites in autistic children: An epigenetic perspective

H Sabit, H Tombuloglu, S Rehman, NB Almandil… - Heliyon, 2021 - cell.com
Gut microbiota has become an issue of great importance recently due to its major role in
autism spectrum disorder (ASD). Over the past three decades, there has been a sustained …

The role of lipidomics in autism spectrum disorder

A El-Ansary, S Chirumbolo, RS Bhat, M Dadar… - Molecular diagnosis & …, 2020 - Springer
Autism spectrum disorder (ASD) is a complex neurodevelopmental syndrome commonly
diagnosed in early childhood; it is usually characterized by impairment in reciprocal …

A thematic review of autism spectrum disorder research in Saudi Arabia: Insights into diagnosis, assessment, and language considerations

M Alasmari, A Alduais, F Qasem - Applied Neuropsychology: Child, 2023 - Taylor & Francis
This study reviews the crucial role of language in Autism Spectrum Disorder (ASD)
diagnosis and assessment in Saudi Arabia. Using tailored search strings, 206 relevant …

Methylenetetrahydrofolate reductase gene variants confer potential vulnerability to autism spectrum disorder in a Saudi community

AH Arab, NA Elhawary - Neuropsychiatric Disease and Treatment, 2019 - Taylor & Francis
Purpose Several interacting genes or single nucleotide polymorphisms (SNPs) are
vulnerable to the risk of autism spectrum disorder (ASD). Here we explored associations …

Association study between genetic variants in vitamin D metabolism related genes and childhood autism spectrum disorder

H Yu, Z Zhang, J Liu, P Hu, Z Liu - Metabolic brain disease, 2020 - Springer
Vitamin D deficiency has been implicated as a risk factor for autism spectrum disorder
(ASD). This case-controlled study was to determine the association between single …

The polymorphisms of candidate pharmacokinetic and pharmacodynamic genes and their pharmacogenetic impacts on the effectiveness of risperidone maintenance …

SAR Shilbayeh, IS Adeen, AS Alhazmi… - European Journal of …, 2024 - Springer
Background Antipsychotics, including risperidone (RIS), are frequently indicated for various
autism spectrum disorder (ASD) manifestations; however,“actionable” PGx testing in …

A snapshot on introspection of autism spectrum disorder

G Kale, V Addepalli, S Joshi - Molecular Biology Reports, 2024 - Springer
Autism spectrum disorder is a neurodevelopmental condition marked by restricted interests
and difficulty with social communication. ASD is characterized by heightened …

A Novel Mutation in the MAP7D3 Gene in Two Siblings with Severe Intellectual Disability and Autistic Traits: Concurrent Assessment of BDNF Functional …

M Kharrat, AB Issa, A Tlili, O Jallouli… - Journal of Molecular …, 2023 - Springer
Intellectual disabilities (ID) and autism spectrum disorders (ASD) are characterized by
extreme genetic and phenotypic heterogeneity. However, understanding this heterogeneity …

Genetic and molecular biology of autism spectrum disorder among Middle East population: a review

Z Rahmani, MR Fayyazi Bordbar, M Dibaj… - Human Genomics, 2021 - Springer
Background Autism spectrum disorder (ASD) is a neurodevelopmental disease,
characterized by impaired social communication, executive dysfunction, and abnormal …